Evidence map›Paper›PMID 25912414›Full record

ArticleInternational journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics2015

Low vitamin D status among pregnant Latin American and Caribbean women with HIV Infection.

Jennifer Jao, Laura Freimanis, Marisa M Mussi-Pinhata, Rachel A Cohen, Jacqueline P Monteiro, Maria L Cruz, Rhoda S Sperling, Andrea Branch, George K Siberry, NISDI LILAC Protocol

Open access · greenAbstract readMulticenter Study
In one paragraph

Article in International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.1field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 10 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 5 institutions in 2 countries.

Jennifer JaoDepartment of Medicine, Icahn School of Medicine at Mount Sinai, New York, NY, USA; Department of Obstetrics, Gynecology, and Reproductive Science, Icahn School of Medicine at Mount Sinai, New York, NY, USA. Electronic address: jennifer.jao@mssm.edu.
Laura FreimanisWestat, Rockville, MD, USA.
Marisa M Mussi-PinhataFaculdade de Medicina, Universidade de São Paulo, Ribeirão Preto, Brazil.
Rachel A CohenWestat, Rockville, MD, USA.
Jacqueline P MonteiroFaculdade de Medicina, Universidade de São Paulo, Ribeirão Preto, Brazil.
Maria L CruzServiço de Doenças Infecciosas e Parasitárias, Hospital Federal dos Servidores do Estado, Rio de Janeiro, Brazil.
Rhoda S SperlingDepartment of Obstetrics, Gynecology, and Reproductive Science, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
Andrea BranchDepartment of Medicine, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
George K SiberryEunice Kennedy Shriver National Institute of Child Health and Human Development, Maternal and Pediatric Infectious Disease Branch, Bethesda, MD, USA.
NISDI LILAC Protocol
Icahn School of Medicine at Mount Sinai · USUniversidade de Ribeirão Preto · BRWestat (United States) · USEunice Kennedy Shriver National Institute of Child Health and Human Development · USHospital Federal dos Servidores do Estado · BR

Funding

Metabolic Effects of In Utero Antiretrovirals on HIV Exposed Uninfected InfantsK23HD070760 · NICHD · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI JAO, JENNIFER · 2012 to 2016
$647k
NICHD INTERNATIONAL PEDIATRIC AND PERINATAL HIV STUDIES NETWORK COORDI-275033345N01HD033345 · NICHD · WESTAT · PI NESEL, CAROL · 2004 to 2006
–
NICHD NIH HHS HHSN267200800001CNICHD NIH HHS K23 HD070760NICHD NIH HHS K23HD070760NICHD NIH HHS N01 HD033345NICHD NIH HHS N01-HD-33345NICHD NIH HHS N01-HD-80001NIDDK NIH HHS HHSN267200800001CNIDDK NIH HHS HHSN267200800001G
6 · The paper itself

Abstract

objectiveTo evaluate the prevalence and predictors of low vitamin D status among pregnant women with HIV infection.

methodsThe present cross-sectional study analyzed repository specimens collected at 12-34 weeks of pregnancy among women enrolled across 17 sites in Latin America and the Caribbean between 2002 and 2009. Logistic regression modeling was used to identify factors associated with low vitamin D status (25-hydroxyvitamin D <30 ng/mL).

resultsAmong 715 women, 218 (30.5%) were vitamin D deficient (<20 ng/mL) and 252 (35.2%) were insufficient (21- /mL). Factors associated with low vitamin D status included residence in subtropical latitudes (adjusted odds ratio [aOR] 1.97, 95% confidence interval [CI] 1.35-2.88), assessment during non-summer seasons (autumn: aOR 1.85, 95% CI 1.20-2.86; spring: 4.3, 2.65-6.95; winter: 10.82, 5.74-20.41), employment (aOR 1.56, 95% CI 1.06-2.38), and assessment before 20 weeks of pregnancy (aOR 1.89, 95% CI 1.18-3.06). Factors protective against low vitamin D status were CD4 count below 200 cells per mm(3) (aOR 0.45, 95% CI 0.26-0.77) and protease inhibitors (aOR 0.62, 95% CI 0.40-0.95).

conclusionLow vitamin D status was prevalent among pregnant women with HIV infection. Further studies are warranted to identify the impact of low maternal vitamin D status.

Indexed as

AdultCaribbean RegionCD4 Lymphocyte CountCross-Sectional StudiesFemaleHIV InfectionsHumansLatin AmericaLogistic ModelsOdds RatioPregnancyPregnancy Complications, InfectiousRisk FactorsVitamin DVitamin D DeficiencyYoung Adult25-hydroxyvitamin DVitamin DCaribbeanHIVLatin AmericaPregnancyVitamin D

Identifiers

PMID25912414
PMCPMC4461462
OpenAlexW2093450480

What OpenQuestion holds

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LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.