Observational studyClinical nutrition (Edinburgh, Scotland)2016
Diet quality and diet patterns in relation to circulating cardiometabolic biomarkers.
Observational study in Clinical nutrition (Edinburgh, Scotland), 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT01853332 (Physical Health in Midlife), which is not on this map. Cited by 35 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Physical Health in Midlife: Influences of Adversity and Relationships Over Time
Who cites it
35 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- The effects of dietary patterns and food groups on symptomatic osteoarthritis: A systematic review.Nutrition & dietetics : the journal of the Dietitians Association of Australia · 2023Pooled it
- Dietary patterns and associations with biomarkers of inflammation in adults: a systematic review of observational studies.Nutrition journal · 2021Pooled it
- Gut Butyrate Reduction in Blood Pressure Is Associated with Other Vegetables, Whole Fruit, Total Grains, and Sodium Intake.Nutrients · 2025Trial
- Trial
- Trial
- Association of Adherence to Various Dietary Patterns With Mortality Among Survivors of Myocardial Infarction: A Prospective Cohort Study.Circulation · 2026Article
- Article
- Ultra-Processed Food Consumption and Systemic Inflammatory Biomarkers: A Scoping Review.Nutrients · 2025Article
- Exercise as a multitarget therapy: modulating myokines, neurotrophins, and inflammation in Parkinson's disease.Frontiers in aging neuroscience · 2025Review
- Association of dietary inflammatory index and systemic inflammatory markers with mortality risk in depressed adults: a mediation analysis of NHANES data.Frontiers in nutrition · 2024Article
- Review
- Multidimensional Health Impact of Multicomponent Exercise and Sustainable Healthy Diet Interventions in the Elderly (MED-E): Study Protocol.Nutrients · 2023Article
- Irisin and Cardiometabolic Disorders in Obesity: A Systematic Review.International journal of inflammation · 2023Review
- Association of plant-based diets with adropin, atherogenic index of plasma, and metabolic syndrome and its components: A cross-sectional study on adults.Frontiers in nutrition · 2023Article
- Irisin reduces inflammatory signaling pathways in inflammation-mediated metabolic syndrome.Molecular and cellular endocrinology · 2022Review
- Reproducibility and validity of diet quality scores derived from food-frequency questionnaires.The American journal of clinical nutrition · 2022Article
- Association of dietary and nutrient patterns with systemic inflammation in community dwelling adults.Frontiers in nutrition · 2022Article
- A Dietary Inflammatory Index and associations with C-reactive protein in a general adult population.European journal of nutrition · 2021Article
- 'Energy-Dense, High-SFA and Low-Fiber' Dietary Pattern Lowered Adiponectin but Not Leptin Concentration of Breast Cancer Survivors.Nutrients · 2021Article
- Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors.
Funding
Abstract
BACKGROUND &
aimsWe examined the effects of diet quality and dietary patterns in relation to biomarkers of risk including leptin, soluble intracellular adhesion molecule 1 (sICAM-1), C-reactive protein (CRP), and irisin.
methodsWe analyzed data from 196 adults cross-sectionally. Dietary patterns were identified by factor analysis and diet quality scores were generated using a validated food-frequency questionnaire.
resultsBoth the alternate healthy eating index-2010 (AHEI-2010) and the Dietary Approaches to Stop Hypertension (DASH) scores were negatively related to CRP, even after controlling for body mass index and total energy intake. Similarly, the prudent diet pattern was negatively related to leptin, sICAM-1, and CRP, whereas the Western diet pattern showed positive associations with these markers; however, after adjusting for all confounders, the associations only remained significant for leptin and sICAM-1. Irisin was positively associated with DASH and the prudent diet after controlling for all confounders (standardized β = 0.23, P = 0.030; standardized β = 0.25, P = 0.021, respectively). Irisin showed positive associations with increasing fruit consumption, whereas the levels of irisin decreased as meat consumption increased.
conclusionsIrisin was directly associated with healthy diet types and patterns. Further studies regarding these mechanisms are warranted. This trial is registered at http://www.clinicaltrials.gov. Identifier: NCT01853332.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.