Evidence map›Paper›PMID 25911598›Full record

ArticleReproductive biomedicine online2015

Impact of whole systems traditional Chinese medicine on in-vitro fertilization outcomes.

Lee E Hullender Rubin, Michael S Opsahl, Klaus E Wiemer, Scott D Mist, Aaron B Caughey

Open access · bronzeAbstract read
In one paragraph

Article in Reproductive biomedicine online, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed, 1 pooled it
11.4field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 1 synthesis or guideline pooled it, 64 citations in OpenAlex.

  1. Pooled it
  2. Trial
  3. Trial
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Whole Systems Research Methods in Health Care: A Scoping Review.Journal of alternative and complementary medicine (New York, N.Y.) · 2019
    Article
  17. Article
  18. Article
  19. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Lee E Hullender RubinOregon College of Oriental Medicine, 75 NW Couch St, Portland, OR, 97210, USA; Oregon Health and Science University, Portland, OR, USA; Portland Acupuncture Studio, Portland, OR, USA. Electronic address: lrubin@ocom.edu.
Michael S OpsahlPoma Fertility, Northwest Center for Reproductive Sciences, Kirkland, WA, USA.
Klaus E WiemerPoma Fertility, Northwest Center for Reproductive Sciences, Kirkland, WA, USA.
Scott D MistOregon Health and Science University, Portland, OR, USA.
Aaron B CaugheyOregon Health and Science University, Portland, OR, USA.
Oregon Health & Science University · USReproductive Science Center · US

Funding

Acupuncture Practitioner Research Education EnhancementR25AT002879 · NCCIH · OREGON COLLEGE OF ORIENTAL MEDICINE · PI ACKERMAN, DEBORAH · 2005 to 2011
$804k
Traditional Chinese Medicine for Fibromyalgia: A Whole Systems TrialK23AT006392 · NCCIH · OREGON HEALTH & SCIENCE UNIVERSITY · PI MIST, SCOTT DAVID · 2011 to 2015
$649k
NCCIH NIH HHS 1K23AT006392NCCIH NIH HHS K23 AT006392NCCIH NIH HHS R25 AT002879
6 · The paper itself

Abstract

Patients undergoing IVF may receive either acupuncture or whole-systems traditional Chinese medicine (WS-TCM) as an adjuvant IVF treatment. WS-TCM is a complex intervention that can include acupuncture, Chinese herbal medicine, dietary, lifestyle recommendations. In this retrospective cohort study, 1231 IVF patient records were reviewed to assess the effect of adjuvant WS-TCM on IVF outcomes compared among three groups: IVF with no additional treatment; IVF and elective acupuncture on day of embryo transfer; or IVF and elective WS-TCM. The primary outcome was live birth. Of 1069 non-donor cycles, WS-TCM was associated with greater odds of live birth compared with IVF alone (adjusted odds ratio [AOR] 2.09; 95% confidence interval [CI] 1.36 to 3.21), or embryo transfer with acupuncture only (AOR 1.62; 95% CI 1.04 to 2.52). Of 162 donor cycles, WS-TCM was associated with increased live births compared with all groups (odds Ratio [OR] 3.72; 95% CI 1.05 to 13.24, unadjusted) or embryo transfer with acupuncture only (OR 4.09; 95% CI: 1.02 to 16.38, unadjusted). Overall, IVF with adjuvant WS-TCM was associated with greater odds of live birth in donor and non-donor cycles. These results should be taken cautiously as more rigorous research is needed.

Indexed as

Fertilization in VitroMedicine, Chinese TraditionalPregnancy RateAcupunctureAdultFemaleHumansPregnancyRetrospective StudiesacupunctureChinese herbal medicineembryo transferin-vitro fertilizationlive birthstraditional Chinese medicine

Identifiers

PMID25911598
PMCPMC4458185
OpenAlexW2052163283

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.