Evidence map›Paper›PMID 25910479›Full record

ArticleInternational journal of clinical pharmacy2015

Critical appraisal of clinical practice guidelines in pediatric infectious diseases.

Kyle John Wilby, Emily Kathleen Black, Claire MacLeod, Matthew Wiens, Tim T Y Lau, Maria A Paiva, Sean Gorman

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Article in International journal of clinical pharmacy, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. A critical review of recent clinical practice guidelines for pediatric urinary tract infection.Canadian Urological Association journal = Journal de l'Association des urologues du Canada · 2018
    Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Kyle John WilbyCollege of Pharmacy, Qatar University, PO Box 2713, Doha, Qatar. kjw@qu.edu.qa.
Emily Kathleen BlackCollege of Pharmacy, Dalhousie University, Halifax, Canada.
Claire MacLeodSurrey Memorial Hospital, Surrey, Canada.
Matthew WiensSchool of Population and Public Health, University of British Columbia, Vancouver, Canada.
Tim T Y LauVancouver General Hospital, Vancouver, Canada.
Maria A PaivaSidra Medical and Research Center, Doha, Qatar.
Sean GormanFaculty of Pharmaceutical Sciences, University of British Columbia, Vancouver, Canada.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThere is a need to critically appraise clinical practice guidelines in order to ensure safe and effective practices are being implemented to optimize patient care. Appraising guidelines within one therapeutic area enable recommendations for improvement during guideline creation and dissemination.

objectivesStudy objectives were to systematically appraise selected published guidelines used in the treatment of pediatric infectious diseases and to make recommendations for improvement throughout the development and dissemination processes.

settingThe study occurred between collaborative academic and practice-based institutions located in Canada and Qatar.

methodsA literature search identified guidelines for management of pediatric infectious diseases from 1997 to 2013. Each guideline was appraised by four independent assessors, according to the appraisal of guidelines for research and evaluation II (AGREE II) instrument. Standardized domain scores were calculated for each guideline and pooled. Final endorsements for use in clinical practice were also determined. Inter-rater reliability was assessed using intraclass correlation coefficients.

main outcome measureStandardized domain scores according to the AGREE II instrument.

resultsTwenty guidelines met inclusion criteria and were appraised. Pooled domain scores were: scope and purpose (69.9), stakeholder involvement (40.1), rigour of development (47.1), clarity of presentation (73.4), applicability (23.7), editorial independence (46.7), and overall assessment (55.8). Two (10%) guidelines were recommended for use without revision, 13 (65%) guidelines were recommended with modifications, and 5 (25%) guidelines were not recommended for implementation into practice. Inter-rater reliability was moderate to good with intra-class correlations of 0.65-0.93 per guideline.

conclusionThe majority of appraised guidelines were moderately rated, with a 25% of guidelines not recommended for use. Strategies for improvement require the involvement of all key stakeholders (caregivers, patients, and allied health professionals), and consideration of facilitators, barriers and resource implications during implementation. Additionally, critical appraisal of guidelines should become standard practice prior to adoption into clinical settings.

Indexed as

Evidence-Based MedicineCommunicable DiseasesHumansPediatricsPractice Guidelines as TopicChildrenClinical practice guidelinesDecision makingEvidence-based medicine

Identifiers

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.