Evidence map›Paper›PMID 25910423›Full record

ReviewBiological psychiatry2015

Electrophysiological endophenotypes in rodent models of schizophrenia and psychosis.

Andrew M Rosen, Timothy Spellman, Joshua A Gordon

Abstract readReview
In one paragraph

Review in Biological psychiatry, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed
2.2field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 38 citations in OpenAlex.

  1. Article
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  5. Article
  6. Review
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  12. Article
  13. Thrombin and theFrontiers in neurology · 2019
    Review
  14. Article
  15. Article
  16. Article
  17. Review
  18. Endophenotype best practices.International journal of psychophysiology : official journal of the International Organization of Psychophysiology · 2017
    Review
  19. Review
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Andrew M RosenDepartment of Psychiatry, College of Physicians and Surgeons, Columbia University, New York, New York.
Timothy SpellmanDepartment of Physiology, College of Physicians and Surgeons, Columbia University, New York, New York.
Joshua A GordonDepartment of Psychiatry, College of Physicians and Surgeons, Columbia University, New York, New York; Division of Integrative Neuroscience, New York State Psychiatric Institute, New York, New York.. Electronic address: jg343@columbia.edu.
Columbia University · USNew York Psychoanalytic Society and Institute · US

Funding

NMDA Receptor Hypofunction in the Amygdala of Schizophrenia PatientsP50MH096891 · NIMH · UNIVERSITY OF PENNSYLVANIA · PI BILKER, WARREN B. · 2012 to 2016
$10.6M
Training in Schizophrenia and Psychotic Disorders: From Animal Models to PatientsT32MH018870 · NIMH · COLUMBIA UNIV NEW YORK MORNINGSIDE · PI Guillermo Horga, Christoph Kellendonk · 1988 to 2026
$9.8M
Mechanisms underlying the functional connectivity deficit in the 22q11 microdeletR01MH096274 · NIMH · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI GOGOS, JOSEPH A · 2012 to 2021
$3.6M
NIMH NIH HHS P50 MH09681NIMH NIH HHS P50 MH096891NIMH NIH HHS R01 MH096274NIMH NIH HHS T32 MH018870
6 · The paper itself

Abstract

Schizophrenia is caused by a diverse array of risk factors and results in a similarly diverse set of symptoms. Electrophysiological endophenotypes lie between risks and symptoms and have the potential to link the two. Electrophysiological studies in rodent models, described here, demonstrate that widely differing risk factors result in a similar set of core electrophysiological endophenotypes, suggesting the possibility of a shared neurobiological substrate.

Indexed as

Disease Models, AnimalEndophenotypesSchizophrenic PsychologyAnimalsBrainGenetic Predisposition to DiseaseHumansNeural InhibitionPsychotic DisordersRatsRisk FactorsSchizophreniaEEGExcitation/inhibition balanceLocal field potentialsOscillationsSchizophreniaSynaptic plasticity

Identifiers

PMID25910423
PMCPMC4444383
OpenAlexW2078998312

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.