ArticlePloS one2015
Health and economic impacts of eight different dietary salt reduction interventions.
Article in PloS one, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 45 papers, 6 of them syntheses that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
45 citing papers in PubMed, 6 syntheses or guidelines pooled it, 72 citations in OpenAlex.
- Modelling health and economic impact of nutrition interventions: a systematic review.European journal of clinical nutrition · 2023Pooled it
- A Systematic Review of Salt Reduction Initiatives Around the World: A Midterm Evaluation of Progress Towards the 2025 Global Non-Communicable Diseases Salt Reduction Target.Advances in nutrition (Bethesda, Md.) · 2021Pooled it
- Salt Reduction Initiatives in the Eastern Mediterranean Region and Evaluation of Progress towards the 2025 Global Target: A Systematic Review.Nutrients · 2021Pooled it
- Effectiveness and Feasibility of Taxing Salt and Foods High in Sodium: A Systematic Review of the Evidence.Advances in nutrition (Bethesda, Md.) · 2020Pooled it
- Cost-effectiveness of salt reduction to prevent hypertension and CVD: a systematic review.Public health nutrition · 2017Pooled it
- Systematic review of dietary salt reduction policies: Evidence for an effectiveness hierarchy?PloS one · 2017Pooled it
- A Mobile Health Salt Reduction Intervention for People With Hypertension: Results of a Feasibility Randomized Controlled Trial.JMIR mHealth and uHealth · 2021Trial
- Cost and cost-effectiveness of a school-based education program to reduce salt intake in children and their families in China.PloS one · 2017Trial
- Population health impacts from the taxation of salt and sugar in the United Kingdom.Public health nutrition · 2025Article
- Stakeholder perspectives on scaling up potassium-enriched salt to reduce cardiovascular disease in Australia: a qualitative study.BMC public health · 2025Article
- Public health economic modelling in evaluations of salt and/or alcohol policies: a systematic scoping review.BMC public health · 2025Article
- Modelling impacts of a salt and sugar tax on hypothetical intra-category food substitutions, BMI and environmental footprints in the UK population.European journal of nutrition · 2024Article
- The development of sodium reduction targets for New Zealand fast foods and a comparison with the current sodium contents of products.Journal of nutritional science · 2024Article
- Examining the Individual Response to a Low-Sodium Diet in Patients with Hypertension: Protocol for a Pilot Randomized Controlled Trial.JMIR research protocols · 2023Article
- Prioritization of intervention domains to prevent cardiovascular disease: a country-level case study using global burden of disease and local data.Population health metrics · 2023Article
- Economic effects of dietary salt reduction policies for cardiovascular disease prevention in Japan: a simulation study of hypothetical scenarios.Frontiers in nutrition · 2023Article
- Estimation of the economic benefits for the public health system related to salt reduction in Costa Rica.PloS one · 2023Article
- Article
- Estimating the cost-effectiveness of the Sodium Reduction in Communities Program.Public health nutrition · 2022Article
- Implementing effective salt reduction programs and policies in low- and middle-income countries: learning from retrospective policy analysis in Argentina, Mongolia, South Africa and Vietnam.Public health nutrition · 2022Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundGiven the high importance of dietary sodium (salt) as a global disease risk factor, our objective was to compare the impact of eight sodium reduction interventions, including feasible and more theoretical ones, to assist prioritisation.
methodsEpidemiological modelling and cost-utility analysis were performed using a Markov macro-simulation model. The setting was New Zealand (NZ) (2.3 million citizens, aged 35+ years) which has detailed individual-level administrative cost data.
resultsOf the most feasible interventions, the largest health gains were from (in descending order): (i) mandatory 25% reduction in sodium levels in all processed foods; (ii) the package of interventions performed in the United Kingdom (UK); (iii) mandatory 25% reduction in sodium levels in bread, processed meats and sauces; (iv) media campaign (as per a previous UK one); (v) voluntary food labelling as currently used in NZ; (vi) dietary counselling as currently used in NZ. Even larger health gains came from the more theoretical options of a "sinking lid" on the amount of food salt released to the national market to achieve an average adult intake of 2300 mg sodium/day (211,000 QALYs gained, 95% uncertainty interval: 170,000-255,000), and from a salt tax. All the interventions produced net cost savings (except counseling--albeit still cost-effective). Cost savings were especially large with the sinking lid (NZ$ 1.1 billion, US$ 0.7 billion). Also the salt tax would raise revenue (up to NZ$ 452 million/year). Health gain per person was greater for Māori (indigenous population) men and women compared to non-Māori.
conclusionsThis study substantially expands on the range of previously modelled salt reduction interventions and suggests that some of these might achieve major health gains and major cost savings (particularly the regulatory interventions). They could also reduce ethnic inequalities in health.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.