SynthesisActa orthopaedica2015
Early subsidence of shape-closed hip arthroplasty stems is associated with late revision. A systematic review and meta-analysis of 24 RSA studies and 56 survival studies.
Synthesis in Acta orthopaedica, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 55 papers, 3 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Link LCU + Lima Delta TT vs DePuy Corail + Pinnacle. A Comparative Study of Stem and Cup Fixation and Polyethylene Wear
Modern Surfaces of the Uncemented Cup in Total Hip Arthroplasty: A Randomized, Clinical Investigation Comparing Two Different Ultra-porous Coated Surfaces of Uncemented Cups Using CT-based Micromotion Analysis and Clinical Evaluation
Who cites it
55 citing papers in PubMed, 3 syntheses or guidelines pooled it, 82 citations in OpenAlex.
- Migration patterns of uncemented femoral stems in hip replacement: a systematic review and meta-analysis of clinical radiostereometric analysis cohort studies.Acta orthopaedica · 2026Pooled it
- 6-month migration sufficient for evaluation of total knee replacements: a systematic review and meta-analysis.Acta orthopaedica · 2023Pooled it
- RSA migration of total knee replacements.Acta orthopaedica · 2018Pooled it
- Similar 2 year migration patterns for a shortened and a distally reduced stem design in uncemented total hip arthroplasty: a randomized controlled trial using radiostereometric analysis.Acta orthopaedica · 2026Trial
- Comparison of 5-year cup and stem migration between ceramic-on-ceramic and ceramic-on-polyethylene bearing in press-fit total hip arthroplasty: a randomised controlled trial using radiostereometric analysis.Hip international : the journal of clinical and experimental research on hip pathology and therapy · 2024Trial
- Migration behaviour of 2 clinically excellent cementless stems with different design rationales: 5-year follow-up of a randomised RSA-study.Hip international : the journal of clinical and experimental research on hip pathology and therapy · 2022Trial
- A model-based radiostereometric analysis (RSA) randomized control trial evaluating the stability of the cementless Taperloc hip stem: the TapHip study.Acta orthopaedica · 2022Trial
- Similar outcome with a new anteverted or a straight standard stem: a randomized study of 72 total hip arthroplasties evaluated with clinical variables, radiostereometry, and DXA up to 2 years.Acta orthopaedica · 2022Trial
- Is the French Paradox cementing philosophy superior to the standard cementing? A randomized controlled radiostereometric trial and comparative analysis.The bone & joint journal · 2022Trial
- Long-term migration of a cementless stem with different bioactive coatings. Data from a "prime" RSA study: lessons learned.Acta orthopaedica · 2020Trial
- Early stabilization of the uncemented Symax hip stem in a 2-year RSA study.Acta orthopaedica · 2020Trial
- Equivalent hip stem fixation by Hi-Fatigue G and Palacos R + G bone cement: a randomized radiostereometric controlled trial of 52 patients with 2 years' follow-up.Acta orthopaedica · 2019Trial
- Femoral stem migration after direct lateral and direct anterior total hip arthroplasty: a prospective cohort study.Canadian journal of surgery. Journal canadien de chirurgieTrial
- Patterns and Risk Factors of Aseptic Loosening in a Hydroxyapatite-Coated Cementless Quadrangular Taper Femoral Stem: A Single-Center Cohort Study.Arthroplasty today · 2026Article
- Vibration assessment of transfemoral implant stability: a longitudinal case series.Journal of orthopaedic surgery and research · 2026Article
- How Femoral Neck Resection Height and Dorr Type Affect the Primary Stability of Cemented Short Stems: An In Vitro Study.Biology · 2026Article
- Precision, Accuracy, and Observer Reliability of Computed Tomography-Based Radiostereometric Analysis in Measuring Femoral Stem Migration In Vitro.Journal of orthopaedic research : official publication of the Orthopaedic Research Society · 2026Article
- Current Uses for Medical Imaging With Orthopaedic Implant Technology.Journal of orthopaedic research : official publication of the Orthopaedic Research Society · 2026Review
- Factors Affecting Early Implant Subsidence after Arthroplasty Using a Cementless Femoral Stem for Displaced Femoral Neck Fracture.Hip & pelvis · 2025Article
- Hybrid glenoid component migration after total shoulder arthroplasty: a cohort study using radiostereometric analysis with 2 years' follow-up.Acta orthopaedica · 2025Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
9 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
background and purposeFew studies have addressed the association between early migration of femoral stems and late aseptic revision in total hip arthroplasty. We performed a meta-regression analysis on 2 parallel systematic reviews and meta-analyses to determine the association between early migration and late aseptic revision of femoral stems. PATIENTS AND
methodsOf the 2 reviews, one covered early migration data obtained from radiostereometric analysis (RSA) studies and the other covered long-term aseptic revision rates obtained from survival studies with endpoint revision for aseptic loosening. Stems were stratified according to the design concept: cemented shape-closed, cemented force-closed, and uncemented. A weighted regression model was used to assess the association between early migration and late aseptic revision, and to correct for confounders. Thresholds for acceptable and unacceptable migration were determined in accordance with the national joint registries (≤ 5% revision at 10 years) and the NICE criteria (≤ 10% revision at 10 years).
results24 studies (731 stems) were included in the RSA review and 56 studies (20,599 stems) were included in the survival analysis review. Combining both reviews for the 3 design concepts showed that for every 0.1-mm increase in 2-year subsidence, as measured with RSA, there was a 4% increase in revision rate for the shape-closed stem designs. This association remained after correction for age, sex, diagnosis, hospital type, continent, and study quality. The threshold for acceptable migration of shape-closed designs was defined at 0.15 mm; stems subsiding less than 0.15 mm in 2 years had revision rates of less than 5% at 10 years, while stems exceeding 0.15 mm subsidence had revision rates of more than 5%.
interpretationThere was a clinically relevant association between early subsidence of shape-closed femoral stems and late revision for aseptic loosening. This association can be used to assess the safety of shape-closed stem designs. The published research is not sufficient to allow us to make any conclusions regarding such an association for the force-closed and uncemented stems.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.