ArticleBiomedical optics express2015
Laser tissue coagulation and concurrent optical coherence tomography through a double-clad fiber coupler.
Article in Biomedical optics express, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
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Who cites it
16 citing papers in PubMed.
- Sensor-integrated dual-clad fiber probe for OCT-guided retinal endolaser photocoagulation.Journal of biomedical optics · 2026Article
- Multimodal Optical Imaging of Ex Vivo Fallopian Tubes to Distinguish Early and Occult Tubo-Ovarian Cancers.Cancers · 2024Article
- Dual modality intravascular catheter system combining pulse-sampling fluorescence lifetime imaging and polarization-sensitive optical coherence tomography.Biomedical optics express · 2024Article
- Towards phase-sensitive optical coherence tomography in smart laser osteotomy: temperature feedback.Lasers in medical science · 2023Article
- Towards OCT-Guided Endoscopic Laser Surgery-A Review.Diagnostics (Basel, Switzerland) · 2023Review
- Double-Clad Fiber-Based Multifunctional Biosensors and Multimodal Bioimaging Systems: Technology and Applications.Biosensors · 2022Review
- Optical Fibre-Enabled Photoswitching for Localised Activation of an Anti-Cancer Therapeutic Drug.International journal of molecular sciences · 2021Article
- Long-range optical coherence tomography with extended depth-of-focus: a visual feedback system for smart laser osteotomy.Biomedical optics express · 2021Article
- Real-time co-localized OCT surveillance of laser therapy using motion corrected speckle decorrelation.Biomedical optics express · 2020Article
- The First In Vivo Needle-Based Optical Coherence Tomography in Human Prostate: A Safety and Feasibility Study.Lasers in surgery and medicine · 2019Article
- Optical coherence tomography-guided laser marking with tethered capsule endomicroscopy in unsedated patients.Biomedical optics express · 2019Article
- Smart laser osteotomy: integrating a pulsed 1064nm fiber laser into the sample arm of a fiber optic 1310nm OCT system for ablation monitoring.Biomedical optics express · 2018Article
- High resolution combined molecular and structural optical imaging of colorectal cancer in a xenograft mouse model.Biomedical optics express · 2018Article
- Intravascular optical coherence tomography [Invited].Biomedical optics express · 2017Article
- Circumferential optical coherence tomography angiography imaging of the swine esophagus using a micromotor balloon catheter.Biomedical optics express · 2016Article
- Image-guidedTechnology in cancer research & treatmentArticle
Corrections and comments
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Authors and funding
7 authors.
Funding
Abstract
Double-clad fiber (DCF) is herein used in conjunction with a double-clad fiber coupler (DCFC) to enable simultaneous and co-registered optical coherence tomography (OCT) and laser tissue coagulation. The DCF allows a single channel fiber-optic probe to be shared: i.e. the core propagating the OCT signal while the inner cladding delivers the coagulation laser light. We herein present a novel DCFC designed and built to combine both signals within a DCF (>90% of single-mode transmission; >65% multimode coupling). Potential OCT imaging degradation mechanisms are also investigated and solutions to mitigate them are presented. The combined DCFC-based system was used to induce coagulation of an ex vivo swine esophagus allowing a real-time assessment of thermal dynamic processes. We therefore demonstrate a DCFC-based system combining OCT imaging with laser coagulation through a single fiber, thus enabling both modalities to be performed simultaneously and in a co-registered manner. Such a system enables endoscopic image-guided laser marking of superficial epithelial tissues or laser thermal therapy of epithelial lesions in pathologies such as Barrett's esophagus.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.