Evidence map›Paper›PMID 25909011›Full record

ArticleBiomedical optics express2015

Assessing breast tumor margin by multispectral photoacoustic tomography.

Rui Li, Pu Wang, Lu Lan, Frank P Lloyd, Craig J Goergen, Shaoxiong Chen, Ji-Xin Cheng

Open access · goldAbstract read
In one paragraph

Article in Biomedical optics express, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 49 papers.

0numbers the graph read from it
0cells of the map it votes in
49citing papers in PubMed
7.1field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

49 citing papers in PubMed, 108 citations in OpenAlex.

  1. Assessment of Breast Tumors Using Multispectral Optoacoustic Tomography in a Surgical Setting.Journal of nuclear medicine : official publication, Society of Nuclear Medicine · 2025
    Trial
  2. Article
  3. Article
  4. Emerging Photoacoustic Imaging Techniques for Peripheral Arterial Disease.Current treatment options in cardiovascular medicine · 2025
    Review
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. The sound of blood: photoacoustic imaging in blood analysis.Medicine in novel technology and devices · 2023
    Article
  12. Article
  13. Journal of biomedical optics · 2023
    Article
  14. Article
  15. Article
  16. Review
  17. Article
  18. Article
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Rui LiWeldon School of Biomedical Engineering, Purdue University, 206 S Martin Jischke Drive., West Lafayette, Indiana, 47907, USA ; Authors contributed equally.
Pu WangWeldon School of Biomedical Engineering, Purdue University, 206 S Martin Jischke Drive., West Lafayette, Indiana, 47907, USA ; Authors contributed equally.
Lu LanWeldon School of Biomedical Engineering, Purdue University, 206 S Martin Jischke Drive., West Lafayette, Indiana, 47907, USA.
Frank P LloydSurgical Oncology- Cascade Metrix/Putman County Hospital, 1542 S Bloomington Street, Greencastle, Indiana, 46135, USA.
Craig J GoergenWeldon School of Biomedical Engineering, Purdue University, 206 S Martin Jischke Drive., West Lafayette, Indiana, 47907, USA ; Purdue University Center for Cancer Research, 201 S. University Street, West Lafayette, Indiana, 47906, USA.
Shaoxiong ChenDepartment of Pathology and Laboratory Medicine, Indiana University School of Medicine, 350 West 11th Street, Indianapolis, Indiana, 46202, USA.
Ji-Xin ChengWeldon School of Biomedical Engineering, Purdue University, 206 S Martin Jischke Drive., West Lafayette, Indiana, 47907, USA ; Department of Chemistry, Purdue University, 560 Oval Drive, West Lafayette, Indiana, 47907, USA ; Purdue University Center for Cancer Research, 201 S. University Street, West Lafayette, Indiana, 47906, USA.
Purdue University West Lafayette · USIndiana University School of Medicine

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

An unmet need exists in high-speed and highly-sensitive intraoperative assessment of breast cancer margin during conservation surgical procedures. Here, we demonstrate a multispectral photoacoustic tomography system for breast tumor margin assessment using fat and hemoglobin as contrasts. This system provides ~3 mm tissue depth and ~125 μm axial resolution. The results agreed with the histological findings. A high sensitivity in margin assessment was accomplished, which opens a compelling way to intraoperative margin assessment.

Indexed as

(000.2700) General science(110.5120) Photoacoustic imaging

Identifiers

PMID25909011
PMCPMC4399666
OpenAlexW2043715571

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.