Evidence map›Paper›PMID 25909000›Full record

ArticleBiomedical optics express2015

Identification of cancerous gastric cells based on common features extracted from hyperspectral microscopic images.

Siqi Zhu, Kang Su, Yumeng Liu, Hao Yin, Zhen Li, Furong Huang, Zhenqiang Chen, Weidong Chen, Ge Zhang, Yihong Chen

Abstract read
In one paragraph

Article in Biomedical optics express, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 1 synthesis or guideline pooled it.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Siqi ZhuKey Laboratory of Optoelectronic Information and Sensing Technologies of Guangdong Higher Education Institutes, Jinan University, Guangzhou, Guangdong 510632, China ; Department of Optoelectronic Engineering, Jinan University, Guangzhou, Guangdong 510632, China.
Kang SuKey Laboratory of Optoelectronic Information and Sensing Technologies of Guangdong Higher Education Institutes, Jinan University, Guangzhou, Guangdong 510632, China ; Department of Optoelectronic Engineering, Jinan University, Guangzhou, Guangdong 510632, China.
Yumeng LiuKey Laboratory of Optoelectronic Information and Sensing Technologies of Guangdong Higher Education Institutes, Jinan University, Guangzhou, Guangdong 510632, China ; Department of Optoelectronic Engineering, Jinan University, Guangzhou, Guangdong 510632, China.
Hao YinKey Laboratory of Optoelectronic Information and Sensing Technologies of Guangdong Higher Education Institutes, Jinan University, Guangzhou, Guangdong 510632, China ; Department of Optoelectronic Engineering, Jinan University, Guangzhou, Guangdong 510632, China.
Zhen LiKey Laboratory of Optoelectronic Information and Sensing Technologies of Guangdong Higher Education Institutes, Jinan University, Guangzhou, Guangdong 510632, China ; Department of Optoelectronic Engineering, Jinan University, Guangzhou, Guangdong 510632, China.
Furong HuangKey Laboratory of Optoelectronic Information and Sensing Technologies of Guangdong Higher Education Institutes, Jinan University, Guangzhou, Guangdong 510632, China ; Department of Optoelectronic Engineering, Jinan University, Guangzhou, Guangdong 510632, China.
Zhenqiang ChenKey Laboratory of Optoelectronic Information and Sensing Technologies of Guangdong Higher Education Institutes, Jinan University, Guangzhou, Guangdong 510632, China ; Department of Optoelectronic Engineering, Jinan University, Guangzhou, Guangdong 510632, China.
Weidong ChenKey Laboratory of Optoelectronic Materials Chemistry and Physics, Fujian Institute of Research on the Structure of Matter, Chinese Academy of Sciences, Fuzhou, Fujian 350002, China.
Ge ZhangKey Laboratory of Optoelectronic Materials Chemistry and Physics, Fujian Institute of Research on the Structure of Matter, Chinese Academy of Sciences, Fuzhou, Fujian 350002, China.
Yihong ChenKey Laboratory of Optoelectronic Information and Sensing Technologies of Guangdong Higher Education Institutes, Jinan University, Guangzhou, Guangdong 510632, China ; Department of Optoelectronic Engineering, Jinan University, Guangzhou, Guangdong 510632, China ; Guangzhou Ante Laser Technology Co. Ltd, Guangzhou, Guangdong 510663, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We construct a microscopic hyperspectral imaging system to distinguish between normal and cancerous gastric cells. We study common transmission-spectra features that only emerge when the samples are dyed with hematoxylin and eosin (H&E) stain. Subsequently, we classify the obtained visible-range transmission spectra of the samples into three zones. Distinct features are observed in the spectral responses between the normal and cancerous cell nuclei in each zone, which depend on the pH level of the cell nucleus. Cancerous gastric cells are precisely identified according to these features. The average cancer-cell identification accuracy obtained with a backpropagation algorithm program trained with these features is 95%.

Indexed as

(110.4234) Multispectral and hyperspectral imaging(170.0170) Medical optics and biotechnology(170.6935) Tissue characterization

Identifiers

PMID25909000
PMCPMC4399655

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.