Evidence map›Paper›PMID 25908999›Full record

ArticleBiomedical optics express2015

Anisotropic aberration correction using region of interest based digital adaptive optics in Fourier domain OCT.

Abhishek Kumar, Tschackad Kamali, René Platzer, Angelika Unterhuber, Wolfgang Drexler, Rainer A Leitgeb

Abstract read
In one paragraph

Article in Biomedical optics express, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

25 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Article
  6. Line-scanning SD-OCT forBiomedical optics express · 2022
    Article
  7. Article
  8. Article
  9. Review
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Adaptive optics imaging of the human retina.Progress in retinal and eye research · 2019
    Review
  16. Article
  17. Biomedical optics express · 2017
    Article
  18. Biomedical optics express · 2017
    Article
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Abhishek KumarCenter of Medical Physics and Biomedical Engineering, Medical University of Vienna, Austria ; Christian Doppler Laboratory for Laser Development and their Application to Medicine and Biology, Waehringer Guertel 18-20 A-1090 Vienna, Austria.
Tschackad KamaliCenter of Medical Physics and Biomedical Engineering, Medical University of Vienna, Austria.
René PlatzerCenter for Pathophysiology, Infectiology and Immunology, Medical University of Vienna, Lazarettgasse 19 A-1090 Vienna, Austria.
Angelika UnterhuberCenter of Medical Physics and Biomedical Engineering, Medical University of Vienna, Austria.
Wolfgang DrexlerCenter of Medical Physics and Biomedical Engineering, Medical University of Vienna, Austria ; Christian Doppler Laboratory for Laser Development and their Application to Medicine and Biology, Waehringer Guertel 18-20 A-1090 Vienna, Austria.
Rainer A LeitgebCenter of Medical Physics and Biomedical Engineering, Medical University of Vienna, Austria ; Christian Doppler Laboratory for Laser Development and their Application to Medicine and Biology, Waehringer Guertel 18-20 A-1090 Vienna, Austria.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In this paper a numerical technique is presented to compensate for anisotropic optical aberrations, which are usually present across the lateral field of view in the out of focus regions, in high resolution optical coherence tomography and microscopy (OCT/OCM) setups. The recorded enface image field at different depths in the tomogram is digitally divided into smaller sub-regions or the regions of interest (ROIs), processed individually using subaperture based digital adaptive optics (DAO), and finally stitched together to yield a final image with a uniform diffraction limited resolution across the entire field of view (FOV). Using this method, a sub-micron lateral resolution is achieved over a depth range of 218 [Formula: see text]for a nano-particle phantom sample imaged using a fiber based point scanning spectral domain (SD) OCM system with a limited depth of focus (DOF) of ~7 [Formula: see text]at a numerical aperture (NA) of 0.6. Thus, an increase in DOF by ~30x is demonstrated in this case. The application of this method is also shown in ex vivo mouse adipose tissue.

Indexed as

(010.1080) Active or adaptive optics(100.2000) Digital image processing(100.3020) Image reconstruction-restoration(100.3175) Interferometric imaging(110.0180) Microscopy(110.4500) Optical coherence tomography

Identifiers

PMID25908999
PMCPMC4399654

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.