Evidence map›Paper›PMID 25908472›Full record

ReviewAdvances in chronic kidney disease2015

Atherosclerotic renal artery stenosis: current status.

Soon Hyo Kwon, Lilach O Lerman

Open access · bronzeAbstract readReview
In one paragraph

Review in Advances in chronic kidney disease, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed, 1 pooled it
1.9field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 1 synthesis or guideline pooled it, 26 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Article
  4. Article
  5. Article
  6. Review
  7. Article
  8. Article
  9. Article
  10. Article
  11. Elevated urinary podocyte-derived extracellular microvesicles in renovascular hypertensive patients.Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association · 2017
    Article
  12. Review
  13. Treatment of In-Stent Restenosis in Patients with Renal Artery Stenosis.Journal of vascular and interventional radiology : JVIR · 2016
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 2 countries.

Soon Hyo KwonDivision of Nephrology and Hypertension, Mayo Clinic, Rochester, MN; and Division of Nephrology, Soonchunhyang University Hospital, Seoul, Korea.
Lilach O LermanDivision of Nephrology and Hypertension, Mayo Clinic, Rochester, MN; and Division of Nephrology, Soonchunhyang University Hospital, Seoul, Korea. Electronic address: lerman.lilach@mayo.edu.
Soonchunhyang University Hospital · KR

Funding

CT imaging for the assessment of kidney injury distal to renal artery stenosisR01DK073608 · NIDDK · MAYO CLINIC ROCHESTER · PI LERMAN, LILACH O · 2006 to 2015
$3.1M
Hypoxia and inflammatory injury in human renovascular hypertensionR01DK100081 · NIDDK · MAYO CLINIC ROCHESTER · PI LERMAN, LILACH O, TEXTOR, STEPHEN C · 2014 to 2018
$2.8M
MSC-derived microvesicles in metabolic syndrome and renovascular diseaseR01DK102325 · NIDDK · MAYO CLINIC ROCHESTER · PI LERMAN, LILACH O · 2015 to 2018
$2.8M
Noninvasive assessment of renal fibrosis using magnetization transfer MRIU01DK104273 · NIDDK · MAYO CLINIC ROCHESTER · PI LERMAN, LILACH O · 2014 to 2018
$1.8M
Low-Energy Shockwave Treatment Distal To Peripheral Vascular DiseaseR21HL121561 · NHLBI · MAYO CLINIC ROCHESTER · PI LERMAN, LILACH O · 2014 to 2015
$434k
NHLBI NIH HHS HL121561NHLBI NIH HHS R21 HL121561NIDDK NIH HHS DK100081NIDDK NIH HHS DK104273NIDDK NIH HHS DK73608NIDDK NIH HHS R01 DK073608NIDDK NIH HHS R01 DK100081NIDDK NIH HHS R01 DK102325NIDDK NIH HHS U01 DK104273
6 · The paper itself

Abstract

Atherosclerotic renal artery stenosis (ARAS) remains a major cause of secondary hypertension and kidney failure. Randomized prospective trials show that medical treatment should constitute the main therapeutic approach in ARAS. Regardless of intensive treatment and adequate blood pressure control, however, renal and extrarenal complications are not uncommon. Yet, the precise mechanisms, accurate detection, and optimal treatment in ARAS remain elusive. Strategies oriented to early detection and targeting these pathogenic pathways might prevent development of clinical end points. Here, we review the results of recent clinical trials, current understanding of the pathogenic mechanisms, novel imaging techniques to assess kidney damage in ARAS, and treatment options.

Indexed as

Angiotensin Receptor AntagonistsAntihypertensive AgentsAtherosclerosisCalcium Channel BlockersDiureticsHumansHypertensionKidneyMagnetic Resonance ImagingMultidetector Computed TomographyRenal Artery ObstructionRenin-Angiotensin SystemAngiotensin Receptor AntagonistsAntihypertensive AgentsCalcium Channel BlockersDiureticsAtherosclerosisHypertensionInflammationIschemiaRenal artery obstruction

Identifiers

PMID25908472
PMCPMC4409651
OpenAlexW1989756286

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.