ArticleReproductive toxicology (Elmsford, N.Y.)2015
Association between urinary biomarkers of exposure to organophosphate insecticides and serum reproductive hormones in men from NHANES 1999-2002.
Article in Reproductive toxicology (Elmsford, N.Y.), 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
12 citing papers in PubMed, 34 citations in OpenAlex.
- Sex and adrenal hormone alteration in Ecuadorian adolescents with home and school proximity to floriculture crop area.Environmental health : a global access science source · 2026Article
- Endocrine-disrupting chemicals in male reproductive health: exposure risks, reproductive toxicity and emerging perspectives.Frontiers in endocrinology · 2026Review
- Sex and adrenal hormones in association with insecticide biomarkers among adolescents living in ecuadorian agricultural communities.International journal of hygiene and environmental health · 2024Article
- The association between urinary organophosphate insecticide metabolites and erectile dysfunction in the United States.International journal of impotence research · 2024Article
- A Comprehensive Analysis of Organic Food: Evaluating Nutritional Value and Impact on Human Health.Foods (Basel, Switzerland) · 2024Review
- Factors affecting urinary organophosphate pesticide metabolite levels among Californian agricultural community members.The Science of the total environment · 2023Article
- Exposure to Organophosphate and Neonicotinoid Insecticides and Its Association with Steroid Hormones among Male Reproductive-Age Farmworkers in Northern Thailand.International journal of environmental research and public health · 2021Article
- Endocrine Disrupting Chemicals and Reproductive Health in Boys and Men.Frontiers in endocrinology · 2021Review
- Effects of Diethyl Phosphate, a Non-Specific Metabolite of Organophosphorus Pesticides, on Serum Lipid, Hormones, Inflammation, and Gut Microbiota.Molecules (Basel, Switzerland) · 2019Article
- Water and soil pollution as determinant of water and food quality/contamination and its impact on male fertility.Reproductive biology and endocrinology : RB&E · 2019Review
- Investigation of associations between exposures to pesticides and testosterone levels in Thai farmers.Archives of environmental & occupational health · 2018Article
- Association between organophosphate insecticide metabolites and lung function in U.S. adults: NHANES 2011-2012.Therapeutic advances in respiratory diseaseArticle
Corrections and comments
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Authors and funding
3 authors at 1 institution in 1 country.
Funding
Abstract
Exposure to organophosphate (OP) insecticides may alter reproductive hormone levels in men and increase the risk for poor reductive health and other adverse health outcomes. However, relevant epidemiology studies in men are limited. We evaluated urinary concentrations of OP metabolites (3,5,6-trichloro-2-pyridinol and six dialkyl phosphates) in relation to serum concentrations of testosterone (T) and estradiol among 356 men aged 20-55 years old from the U.S. National Health and Nutrition Examination Survey. Biomarkers were detected in greater than 50% of the samples, except for diethyldithiophosphate, dimethylphosphate, and dimethyldithiophosphate. In adjusted regression models, we observed a statistically significant inverse relationship between diethyl phosphate (DEP) and T when DEP was modeled as either a continuous or categorical variable. These findings add to the limited evidence that exposure to certain OP insecticides is linked to altered T in men, which may have important implications for male health.
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