ArticleInternational forum of allergy & rhinology2015
Does comorbid anxiety predict quality of life outcomes in patients with chronic rhinosinusitis following endoscopic sinus surgery?
Article in International forum of allergy & rhinology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers, 2 of them syntheses that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
21 citing papers in PubMed, 2 syntheses or guidelines pooled it, 38 citations in OpenAlex.
- Advanced Age in Sinus Surgery: Diminished Symptom Gains but Enhanced Surgical Durability in Chronic Rhinosinusitis.Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery · 2025Pooled it
- Sino-Nasal outcome test-22 outcomes after sinus surgery: A systematic review and meta-analysis.The Laryngoscope · 2018Pooled it
- Predictive factors of a beneficial quality of life outcome in patients undergoing primary sinonasal surgery: a population-based prospective cohort study.European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2018Trial
- Hyperactive basolateral amygdala mediates comorbid anxiety in chronic rhinosinusitis.Journal of neuroinflammation · 2026Article
- Evaluation of Anxiety and Depression in Patients with Chronic Rhinosinusitis with Nasal Polyps.Journal of inflammation research · 2026Article
- ASSOCIATION BETWEEN SYMPTOM SEVERITY AND INTENSITY OF ACUTE PSYCHOLOGICAL DISTRESS IN NEWLY DIAGNOSED PATIENTS WITH CHRONIC RHINITIS AND CHRONIC RHINOSINUSITIS.Acta clinica Croatica · 2023Article
- Cumulative comorbidity burden does not worsen outcomes in management of chronic rhinosinusitis.International forum of allergy & rhinology · 2022Article
- Pain Catastrophizing and Quality of Life in Adults With Chronic Rhinosinusitis.The Laryngoscope · 2021Article
- Effect of Functional Endoscopic Sinus Surgery on Outcomes in Chronic Rhinosinusitis.Current allergy and asthma reports · 2020Review
- Article
- Symptom importance, patient expectations, and satisfaction in chronic rhinosinusitis.International forum of allergy & rhinology · 2019Article
- Effect of generalized anxiety disorders on the success of pessary treatment for pelvic organ prolapse.International urogynecology journal · 2018Article
- The impact of chronic airway disease on symptom severity and global suffering in Canadian rhinosinusitis patients.Journal of otolaryngology - head & neck surgery = Le Journal d'oto-rhino-laryngologie et de chirurgie cervico-faciale · 2018Article
- Article
- Comparing surgeon outcomes in endoscopic sinus surgery for chronic rhinosinusitis.The Laryngoscope · 2017Observational
- Longitudinal improvement and stability of olfactory function in the evaluation of surgical management for chronic rhinosinusitis.International forum of allergy & rhinology · 2016Observational
- Improvements in psychological dysfunction after endoscopic sinus surgery for patients with chronic rhinosinusitis.International forum of allergy & rhinology · 2016Observational
- A survey on chronic rhinosinusitis: opinions from experts of 50 countries.European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2016Article
- Patient-centered decision making: the role of the baseline SNOT-22 in predicting outcomes for medical management of chronic rhinosinusitis.International forum of allergy & rhinology · 2016Article
- Productivity outcomes following endoscopic sinus surgery for recurrent acute rhinosinusitis.The Laryngoscope · 2016Article
Corrections and comments
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Authors and funding
3 authors at 1 institution in 1 country.
Funding
Abstract
backgroundApproximately 25% of patients with chronic rhinosinusitis (CRS) have comorbid anxiety and both conditions independently decrease quality of life (QOL). QOL outcomes for CRS and depression have garnered the majority of research attention, but efforts to better understand the impact of anxiety disorders on QOL are increasing. We evaluated the role of comorbid anxiety in patients with CRS undergoing endoscopic sinus surgery (ESS).
methodsAdult patients (n = 148) with CRS with and without comorbid anxiety were prospectively enrolled into a treatment outcomes investigation. History of comorbid anxiety was retrospectively identified (n = 30; 20%) and preoperative and postoperative QOL (Rhinosinusitis Disability Index [RSDI], and 22-item Sino-Nasal Outcome Test [SNOT-22]) scores were compared to patients without comorbid anxiety.
resultsCompared to patients without anxiety, patients with anxiety were found to be younger (p = 0.02) and have a higher prevalence of female gender (p = 0.05), diabetes mellitus (p < 0.001), depression (p < 0.001), and tobacco use (p = 0.03). Participants with comorbid anxiety reported significantly worse preoperative psychological dysfunction as measured by SNOT-22 subdomain scores (p = 0.02), as well as worse preoperative functional (p = 0.04) and emotional (p = 0.001) impairment as evaluated by RSDI subdomain scores. After adjustment for other cofactors, patients with anxiety improved significantly less on SNOT-22 total scores compared to participants without anxiety after ESS (p = 0.02).
conclusionAnxiety occurs with higher prevalence in patients with CRS and the presence of comorbid anxiety is associated with worse preoperative QOL and reduced QOL improvement following ESS. These findings warrant improvement in screening, diagnosis, and treatment for patients with CRS and comorbid anxiety.
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