ArticleBMC musculoskeletal disorders2015
Bioimpedance spectroscopy for swelling evaluation following total knee arthroplasty: a validation study.
Article in BMC musculoskeletal disorders, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 4 registered trials, which are not on this map. Cited by 20 papers, 2 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Validation of a Procedure Using Bioimpedance to Measure the Edema of Lower Leg of Patients After Total Knee Surgery
Cross Therapy Registry - Edema Post Market Clinical Follow-up of Safety and Patient Outcomes for Subjects Undergoing Peroneal Nerve Stimulation by Geko™.
Cross Therapy Registry - Oedema Post Market Clinical Follow-up of Safety and Patient Outcomes for Subjects Undergoing Peroneal Nerve Stimulation by Geko™. CTR-Oedema-EU
Swelling Management After Total Knee Arthroplasty
Who cites it
20 citing papers in PubMed, 2 syntheses or guidelines pooled it, 38 citations in OpenAlex.
- The diagnostic accuracy of soft tissue oedema measurements: a systematic review and best-evidence synthesis.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2026Pooled it
- Should compression bandage be performed after total knee arthroplasty? A meta-analysis of randomized controlled trials.Journal of orthopaedic surgery and research · 2020Pooled it
- Efficacy of kinesiotaping during rehabilitation following total knee arthroplasty: a prospective randomised controlled trial.Journal of rehabilitation medicine · 2026Trial
- Impact of compression stockings on leg swelling after arthroscopy - a prospective randomised pilot study.BMC musculoskeletal disorders · 2019Trial
- Reliability of bioimpedance spectroscopy in the upper trapezius muscle.Journal of electromyography and kinesiology : official journal of the International Society of Electrophysiological Kinesiology · 2026Article
- Automated Optical 3d Scanner to Assess Postoperative Edema Following Forefoot Surgery.Journal of foot and ankle research · 2026Observational
- Analysis of biological systems using bioimpedance spectroscopy: a critical review of technological convergence and translational challenges.Frontiers in bioengineering and biotechnology · 2026Review
- Segmental bioimpedance and anthropometry improve machine learning prediction of grip strength in healthy young adults.Frontiers in bioengineering and biotechnology · 2026Article
- Efficacy of Kinesiotaping on Functional Outcomes, Pain, and Edema in the Early Rehabilitation After Total Knee Arthroplasty Surgery: A Randomized Controlled Trial.Journal of clinical medicine · 2024Article
- Article
- Assessment of the Efficiency of Measuring Foot and Ankle Edema with a 3D Portable Scanner.Bioengineering (Basel, Switzerland) · 2023Article
- Whole-body phase angle correlates with pre-operative markers in total joint arthroplasty.Journal of electrical bioimpedance · 2023Article
- Localized Multi-Site Knee Bioimpedance as a Predictor for Knee Osteoarthritis Associated Pain Within Older Adults During Free-Living.IEEE open journal of engineering in medicine and biology · 2023Article
- Difference in Bioimpedance Across the Knee in Un-Injured Young Adults.The Iowa orthopaedic journal · 2023Article
- Body Composition Changes in the Immediate Peri-operative Period Following Total Joint Arthroplasty.Journal of electrical bioimpedance · 2022Article
- Article
- The Therapeutic Effects of Goreisan, a Traditional Japanese Herbal Medicine, on Lower-Limb Lymphedema after Lymphadenectomy in Gynecologic Malignancies: A Case Series Study.Evidence-based complementary and alternative medicine : eCAM · 2020Article
- The relationship between lower extremity swelling, quadriceps strength, and functional performance following total knee arthroplasty.The Knee · 2019Observational
- Wearable Vector Electrical Bioimpedance System to Assess Knee Joint Health.IEEE transactions on bio-medical engineering · 2017Article
- The increase in hydric volume is associated to contractile impairment in the calf after the world's most extreme mountain ultra-marathon.Extreme physiology & medicine · 2015Article
Corrections and comments
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Authors and funding
5 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThe evaluation of swelling is important for the outcome of total knee arthroplasty (TKA) surgery. The circumference or volume measurements are applicable at the bedside of the patient but are altered by muscular atrophy and the post-surgical dressing. Bioimpedance spectroscopy might overcome these limitations; however, it should be validated. This study aimed to explore the validity, the reliability and the responsiveness of bioimpedance spectroscopy for measuring swelling after TKA.
methodsThe degree of swelling in 25 patients undergoing TKA surgery was measured using bioimpedance spectroscopy (BIS R0), knee circumference and limb volume. The measurements were performed on D-1 (day before surgery), D + 2 (2 days after surgery) and D + 8 (8 days after surgery). The BIS R0 measurements were repeated twice, alternating between two evaluators. The percentage of the difference between the limbs was calculated for BIS R0, circumference and volume. The intra- and inter-observer intraclass correlation coefficients (ICCs), limits of agreement (LOA), effect size (Cohen's d), correlations between the methods and diagnostic sensitivity were calculated.
resultsBIS R0, circumference and volume detected swelling < 3.5% at D-1. The swelling at D2 and D8 was greater with BIS R0 [mean (SD) 29.9% (±9.8) and 38.27 (±7.8)] than with volume [14.7 (±9.5) and 14.9 (±8.2)] and circumference [11.1 (±5.7) and 11.7 (±4.1)]. The BIS R0 intra- and inter-evaluator ICCs ranged from 0.89 to 0.99, whereas the LOA were < 5.2%. The BIS R0 correlation was 0.73 with volume and 0.75 with circumference. The BIS R0 Cohen's d was 3.32 for the D-1-D2 evolution. The diagnostic sensitivity was 83% D2 and 96% at D8.
conclusionBioimpedance is a valid method for the evaluation of swelling following TKA. BIS R0 also demonstrated excellent intra- and inter-evaluator reliability. The diagnostic sensitivity and responsiveness is superior to that of concurrent methods. BIS R0 is an efficient method for post-surgical follow up at the bedside of the patient. The measurement of BIS R0 is a straightforward, valid, reliable and responsive method for lower limb swelling following TKA surgery that could be used in clinics and research.
trial registrationClinicalTrials.gov Identifier: NCT00627770.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.