ArticleBiomedical engineering online2015
Model demonstrates functional purpose of the nasal cycle.
Article in Biomedical engineering online, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
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Who cites it
14 citing papers in PubMed.
- The effects of unilateral nostril breathing on brain functional network activity: a pilot study.Journal of neuroengineering and rehabilitation · 2025Article
- Creating nasal cycle simulations by processing MRI and CT scan data with image morphing algorithms.Scientific reports · 2025Article
- Assessing Nasal Epithelial Dynamics: Impact of the Natural Nasal Cycle on Intranasal Spray Deposition.Pharmaceuticals (Basel, Switzerland) · 2024Article
- New insights into the variability of upper airway morphology in modern humans.Journal of anatomy · 2023Article
- Transnasal-brain delivery of nanomedicines for neurodegenerative diseases.Frontiers in drug delivery · 2023Review
- The Utility and Acceptability of a New Noninvasive Ventilatory Assist Device, Rest-Activity Cycler-Positive Airways Pressure, During Exercise in a Population of Healthy Adults: Cohort Study.JMIR rehabilitation and assistive technologies · 2022Article
- Using the Intranasal Route to Administer Drugs to Treat Neurological and Psychiatric Illnesses: Rationale, Successes, and Future Needs.CNS drugs · 2022Review
- EEG signatures change during unilateral Yogi nasal breathing.Scientific reports · 2022Article
- Essentials in saline pharmacology for nasal or respiratory hygiene in times of COVID-19.European journal of clinical pharmacology · 2021Review
- Computer simulations show that Neanderthal facial morphology represents adaptation to cold and high energy demands, but not heavy biting.Proceedings. Biological sciences · 2018Article
- A Case of Synchronised Pupillary and Nasal Cycling: Evidence for a Central Autonomic Pendulum?Neuro-ophthalmology (Aeolus Press) · 2017Article
- Measuring and Characterizing the Human Nasal Cycle.PloS one · 2016Article
- Heart Rate Variability during Nostril-Regulated Yoga Breathing: A Randomized Crossover Study.International journal of yogaArticle
- Effect of Nasal Dominance on Pulmonary Function Test and Heart Rate: A Pilot Study.International journal of yogaArticle
Corrections and comments
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Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundDespite the occurrence of the nasal cycle being well documented, the functional purpose of this phenomenon is not well understood. This investigation seeks to better understand the physiological objective of the nasal cycle in terms of airway health through the use of a computational nasal air-conditioning model.
methodA new state-variable heat and water mass transfer model is developed to predict airway surface liquid (ASL) hydration status within each nasal airway. Nasal geometry, based on in-vivo magnetic resonance imaging (MRI) data is used to apportion inter-nasal air flow.
resultsThe results demonstrate that the airway conducting the majority of the airflow also experiences a degree of ASL dehydration, as a consequence of undertaking the bulk of the heat and water mass transfer duties. In contrast, the reduced air conditioning demand within the other airway allows its ASL layer to remain sufficiently hydrated so as to support continuous mucociliary clearance.
conclusionsIt is quantitatively demonstrated in this work how the nasal cycle enables the upper airway to accommodate the contrasting roles of air conditioning and the removal of entrapped contaminants through fluctuation in airflow partitioning between each airway.
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