Evidence map›Paper›PMID 25907459›Full record

ReviewNature reviews. Immunology2015

The impact of diet on asthma and allergic diseases.

Valerie Julia, Laurence Macia, David Dombrowicz

Registry-linked trialAbstract readReview
PubMed Publisher
In one paragraph

Review in Nature reviews. Immunology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05728385 (Impact of Modified Specific Carbohydrate Diet on Bronchial Asthma Control in Children), which is not on this map. Cited by 122 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
122citing papers in PubMed, 2 pooled it
17.3field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05728385 naunknown statusnot on this mapstarted 2023, after this paper: background citation

Impact of Modified Specific Carbohydrate Diet on Bronchial Asthma Control in Children

TypeinterventionalSponsorTanta UniversityRan2023 to 2024Enrolled60ConditionsAsthma in ChildrenArmsModified Specific carbohydrate diet for 3 months
3 · Its place in the literature

Who cites it

122 citing papers in PubMed, 2 syntheses or guidelines pooled it, 250 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Trial
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  6. Article
  7. Article
  8. Article
  9. Why Every Asthma Patient Tells a Different Story.Journal of clinical medicine · 2025
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  10. Review
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  13. Review
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62 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 3 institutions in 2 countries.

Valerie Julia1] Centre Nationale de la Recherche Scientifique (CNRS) Unité mixte de Recherche 7275, 06560 Valbonne, France. [2] Institut National de la santé et de la recherche médicale (Inserm) U1080, France. [3] University of Nice Sophia-Antipolis, France.
Laurence MaciaDepartment of Immunology, Monash University, Clayton, Victoria 3800, Australia.
David Dombrowicz1] Inserm U1011, France. [2] Institut Pasteur de Lille, 1 rue du Professeur Calmette, 59019 Lille cedex, France. [3] Lille 2 University, Lille, France. [4] European Genomic Institute for Diabetes, Lille, France.
Centre National de la Recherche Scientifique · FRInserm · FRMonash University · AU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The incidence of allergic diseases is increasing, both in developed and developing countries, concomitantly with the rise in living standards and the adoption of a 'western lifestyle'. For two decades, the hygiene hypothesis - which proposes that the lack of early childhood exposure to infectious agents increases susceptibility to allergic diseases in later life - provided the conceptual framework for unravelling the mechanisms that could account for the increased incidence of allergic diseases. In this Review, we discuss recent evidence that highlights the role of diet as a key factor influencing immune homeostasis and the development of allergic diseases through a complex interplay between nutrients, their metabolites and immune cell populations. Although further investigations are still required to understand these complex relationships, recent data have established a possible connection between metabolic homeostasis and allergic diseases.

Indexed as

DietFoodAllergensAsthmaBreast FeedingHomeostasisHumansHygiene HypothesisHypersensitivityImmune SystemObesityAllergens

Identifiers

PMID25907459
OpenAlexW2036396112

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.