Evidence map›Paper›PMID 25907212›Full record

ArticleOccupational and environmental medicine2015

Cleaning products and short-term respiratory effects among female cleaners with asthma.

David Vizcaya, Maria C Mirabelli, David Gimeno, Josep-Maria Antó, George L Delclos, Marcela Rivera, Ramon Orriols, Lourdes Arjona, Felip Burgos, Jan-Paul Zock

Open access · greenAbstract read
In one paragraph

Article in Occupational and environmental medicine, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
4.3field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 47 citations in OpenAlex.

  1. Cleaning products and classes associated with poor respiratory health.Environmental science and pollution research international · 2026
    Article
  2. Article
  3. Review
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  5. Article
  6. Article
  7. Review
  8. Article
  9. Article
  10. Professional cleaning and risk of asthma - a Danish nationwide register-based study.Scandinavian journal of work, environment & health · 2022
    Article
  11. Article
  12. Article
  13. Article
  14. A Practical Approach to Severe Asthma in Children.Annals of the American Thoracic Society · 2018
    Review
  15. Health risks in the cleaning industry: a Belgian census-linked mortality study (1991-2011).International archives of occupational and environmental health · 2018
    Article
  16. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

10 authors at 4 institutions in 4 countries.

David VizcayaCentre for Research in Environmental Epidemiology (CREAL), Barcelona, Catalonia, Spain CIBER Epidemiología y Salud Pública (CIBERESP), Madrid, Spain University of Montreal Hospital Research Centre (CRCHUM), Montreal, Canada Departament de Ciències Experimental i de la Salut, Universitat Pompeu Fabra (UPF), Barcelona, Catalonia, Spain.
Maria C MirabelliCentre for Research in Environmental Epidemiology (CREAL), Barcelona, Catalonia, Spain.ORCID http://orcid.org/0000-0002-3540-0085
David GimenoThe University of Texas Health Science Center at Houston, School of Public Health, San Antonio Regional Campus, San Antonio, Texas, USA Center for Research in Occupational Health (CiSAL), University Pompeu Fabra (UPF), Barcelona, Catalonia, Spain.
Josep-Maria AntóCentre for Research in Environmental Epidemiology (CREAL), Barcelona, Catalonia, Spain CIBER Epidemiología y Salud Pública (CIBERESP), Madrid, Spain Departament de Ciències Experimental i de la Salut, Universitat Pompeu Fabra (UPF), Barcelona, Catalonia, Spain IMIM (Hospital del Mar Medical Research Institute), Barcelona, Catalonia, Spain.
George L DelclosCIBER Epidemiología y Salud Pública (CIBERESP), Madrid, Spain Center for Research in Occupational Health (CiSAL), University Pompeu Fabra (UPF), Barcelona, Catalonia, Spain IMIM (Hospital del Mar Medical Research Institute), Barcelona, Catalonia, Spain The University of Texas School of Public Health, Houston, Texas, USA.
Marcela RiveraDepartament de Ciències Experimental i de la Salut, Universitat Pompeu Fabra (UPF), Barcelona, Catalonia, Spain.
Ramon OrriolsCentro de Investigación en Red de Enfermedades Respiratorias (CIBERES), Instituto de Salud Carlos III (ISCIII), Bunyola, Majorca, Balearic Islands, Spain Servei de Pneumologia, Hospitals de Girona i Salt. Institut d'Investigació Biomòdica de Girona (IDIBGI), Girona, Catalonia, Spain.
Lourdes ArjonaCentre for Research in Environmental Epidemiology (CREAL), Barcelona, Catalonia, Spain CIBER Epidemiología y Salud Pública (CIBERESP), Madrid, Spain IMIM (Hospital del Mar Medical Research Institute), Barcelona, Catalonia, Spain.
Felip BurgosCentro de Investigación en Red de Enfermedades Respiratorias (CIBERES), Instituto de Salud Carlos III (ISCIII), Bunyola, Majorca, Balearic Islands, Spain Servei de Pneumologia, Hospital Clínic, IDIBAPS, Barcelona, Catalonia, Spain.
Jan-Paul ZockCentre for Research in Environmental Epidemiology (CREAL), Barcelona, Catalonia, Spain CIBER Epidemiología y Salud Pública (CIBERESP), Madrid, Spain Departament de Ciències Experimental i de la Salut, Universitat Pompeu Fabra (UPF), Barcelona, Catalonia, Spain Netherlands Institute for Health Services Research (NIVEL), Utrecht, The Netherlands.
Universitat Pompeu Fabra · ESCenter for Research in Environmental Epidemiology · ESInstituto de Salud Carlos III · ESThe University of Texas Health Science Center at San Antonio · US

Funding

NIOSH CDC HHS T42 OH008421
6 · The paper itself

Abstract

objectiveWe evaluated the short-term effects of exposure to cleaning products on lung function and respiratory symptoms among professional cleaning women.

methodsTwenty-one women with current asthma and employed as professional cleaners participated in a 15-day panel study. During 312 person-days of data collection, participants self-reported their use of cleaning products and respiratory symptoms in daily diaries and recorded their forced expiratory volume in 1 s (FEV1) and peak expiratory flow (PEF) three times per day using a handheld spirometer. We evaluated associations of cleaning product use with upper and lower respiratory tract symptoms using Poisson mixed regression models and with changes in FEV1 and PEF using linear mixed regression analyses.

resultsParticipants reported using an average of 2.4 cleaning products per day, with exposure to at least one strong irritant (eg, ammonia, bleach, hydrochloric acid) on 56% of person-days. Among participants without atopy, lower respiratory tract symptoms were associated with the use of hydrochloric acid and detergents. Measurements of FEV1 and PEF taken in the evening were 174 mL (95% CI 34 to 314) and 37 L/min (CI 4 to 70), respectively, lower on days when three or more sprays were used. Evening and next morning FEV1 were both lower following the use of hydrochloric acid (-616 and -526 mL, respectively) and solvents (-751 and -1059 mL, respectively). Diurnal variation in FEV1 and PEF increased on days when ammonia and lime-scale removers were used.

conclusionsThe use of specific cleaning products at work, mainly irritants and sprays, may exacerbate asthma.

Indexed as

Pulmonary VentilationAdultAerosolsAmmoniaAsthmaDetergentsFemaleForced Expiratory VolumeHumansHydrochloric AcidIrritantsLongitudinal StudiesLungMiddle AgedOccupational DiseasesOccupational ExposureAerosolsAmmoniaDetergentsHydrochloric AcidIrritantsSolvents

Identifiers

PMID25907212
PMCPMC8856568
OpenAlexW2100267483

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.