Evidence map›Paper›PMID 25906833›Full record

ArticleCancer2015

Paths to health equity: Local area variation in progress toward eliminating breast cancer mortality disparities, 1990-2009.

George Rust, Shun Zhang, Khusdeep Malhotra, Leroy Reese, Luceta McRoy, Peter Baltrus, Lee Caplan, Robert S Levine

Abstract read
In one paragraph

Article in Cancer, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Rural-Urban Differences in Breast Cancer Stage at Diagnosis.Women's health reports (New Rochelle, N.Y.) · 2022
    Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Review
  14. Article
  15. Article
  16. Article
  17. Article
  18. Perspective: Hope for Health Equity.Ethnicity & disease · 2017
    Article
  19. Article
  20. Disparities in Use of Human Epidermal Growth Hormone Receptor 2-Targeted Therapy for Early-Stage Breast Cancer.Journal of clinical oncology : official journal of the American Society of Clinical Oncology · 2016
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

George RustNational Center for Primary Care, Morehouse School of Medicine, Atlanta, Georgia.
Shun ZhangNational Center for Primary Care, Morehouse School of Medicine, Atlanta, Georgia.
Khusdeep MalhotraNational Center for Primary Care, Morehouse School of Medicine, Atlanta, Georgia.
Leroy ReeseNational Center for Primary Care, Morehouse School of Medicine, Atlanta, Georgia.
Luceta McRoyNational Center for Primary Care, Morehouse School of Medicine, Atlanta, Georgia.
Peter BaltrusNational Center for Primary Care, Morehouse School of Medicine, Atlanta, Georgia.
Lee CaplanDepartment of Community Health and Preventive Medicine, Morehouse School of Medicine, Atlanta, Georgia.
Robert S LevineDepartment of Family and Community Medicine, Meharry Medical College, Nashville, Tennessee.

Funding

Morehouse School of Medicine Center of Excellence Research Endowment ProgramS21MD000101 · NIMHD · MOREHOUSE SCHOOL OF MEDICINE · PI MONTGOMERY-RICE, VALERIE C. · 2001 to 2015
$74.3M
TRAINING AND CAREER DEVELOPMENTU54CA118948 · NCI · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI UPENDER MANNE · 2005 to 2026
$26.6M
Research Desogn and Biostatistics CoreU54MD007588 · NIMHD · MOREHOUSE SCHOOL OF MEDICINE · PI MAYBERRY, ROBERT M · 2012 to 2018
$24.8M
Research Training & Career Development ProgramU54CA118638 · NCI · MOREHOUSE SCHOOL OF MEDICINE · PI Desiree Avia Rivers · 2005 to 2026
$22.7M
Research Education CoreU54CA118623 · NCI · TUSKEGEE UNIVERSITY · PI Vivian L Carter, TIMOTHY TURNER · 2005 to 2026
$20.2M
Training/Education CoreP20MD000516 · NIMHD · MEHARRY MEDICAL COLLEGE · PI LEVINE, ROBERT A · 2003 to 2013
$14.2M
Women's Health Intervention StudyP20MD006881 · NIMHD · MOREHOUSE SCHOOL OF MEDICINE · PI MAYBERRY, ROBERT M · 2012 to 2016
$6.0M
INFRASTRUCTURE IIG12MD007585 · NIMHD · TUSKEGEE UNIVERSITY · PI YATES, CLAYTON · 2012 to 2016
$4.6M
Mid-Career Transition -- Mapping Paths to Success in Achieving Community-Level HeK18HS022444 · AHRQ · MOREHOUSE SCHOOL OF MEDICINE · PI RUST, GEORGE S · 2013 to 2014
$532k
AHRQ HHS K18 HS022444AHRQ HHS K18HS022444NCI NIH HHS U54 CA118623NCI NIH HHS U54 CA118638NCI NIH HHS U54 CA118948NIMHD NIH HHS 1P20MD006881-02NIMHD NIH HHS 8U54MD007588NIMHD NIH HHS G12 MD007585NIMHD NIH HHS P20 MD000516NIMHD NIH HHS P20 MD006881NIMHD NIH HHS S21 MD000101NIMHD NIH HHS U54 MD007588
6 · The paper itself

Abstract

backgroundUS breast cancer deaths have been declining since 1989, but African American women are still more likely than white women to die of breast cancer. Black/white disparities in breast cancer mortality rate ratios have actually been increasing.

methodsAcross 762 US counties with enough deaths to generate reliable rates, county-level, age-adjusted breast cancer mortality rates were examined for women who were 35 to 74 years old during the period of 1989-2010. Twenty-two years of mortality data generated twenty 3-year rolling average data points, each centered on a specific year from 1990 to 2009. Mixed linear models were used to group each county into 1 of 4 mutually exclusive trend patterns. The most recent 3-year average black breast cancer mortality rate for each county was also categorized as being worse or not worse than the breast cancer mortality rate for the total US population.

resultsMore than half of the counties (54%) showed persistent, unchanging disparities. Roughly 1 in 4 (24%) had a divergent pattern of worsening black/white disparities. However, 10.5% of the counties sustained racial equality over the 20-year period, and 11.7% of the counties actually showed a converging pattern from high disparities to greater equality. Twenty-three counties had 2008-2010 black mortality rates better than the US average mortality rate.

conclusionsDisparities are not inevitable. Four US counties have sustained both optimal and equitable black outcomes as measured by both absolute (better than the US average) and relative benchmarks (equality in the local black/white rate ratio) for decades, and 6 counties have shown a path from disparities to health equity.

Indexed as

Health Status DisparitiesBlack or African AmericanBlack PeopleBreast NeoplasmsFemaleHumansTime FactorsWhite Peoplebreast cancerdisparitiesequitylocal-area variationmortality trendsrace

Identifiers

PMID25906833
PMCPMC4540479

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.