Evidence map›Paper›PMID 25906791›Full record

Trial reportAge and ageing2015

Randomised controlled trial of the effectiveness of community group and home-based falls prevention exercise programmes on bone health in older people: the ProAct65+ bone study.

Rachel L Duckham, Tahir Masud, Rachael Taylor, Denise Kendrick, Hannah Carpenter, Steve Iliffe, Richard Morris, Heather Gage, Dawn A Skelton, Susie Dinan-Young and 1 more

Registry-linked trialOpen access · bronzeAbstract readMulticenter StudyRandomized Controlled Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in Age and ageing, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05541432 (Finding the Optimal Resistance Training Intensity For Your Bones), which is not on this map. Cited by 14 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed, 2 pooled it
7.9field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05541432 nacompletednot on this mapstarted 2022, after this paper: background citation

Finding the Optimal Resistance Training Intensity For Your Bones: A Randomized Controlled Trial (FORTIFY Bones)

TypeinterventionalSponsorUniversity of WaterlooRan2022 to 2026Enrolled324ConditionsOsteoporosis, OsteopeniaArmsSupervised strength training (group 1), Supervised strength training (group 2), Home exercise
3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 2 syntheses or guidelines pooled it, 42 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Trial
  4. Trial
  5. Article
  6. Impact of physical activity programs and services for older adults: a rapid review.The international journal of behavioral nutrition and physical activity · 2022
    Review
  7. Article
  8. Article
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  10. Article
  11. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 7 institutions in 2 countries.

Rachel L DuckhamSchool of Sport, Exercise and Health Sciences, Loughborough University, Loughborough, UK Present Address: Centre for Physical Activity and Nutrition Research, Deakin University, Australia.
Tahir MasudHealthcare for Older People, Nottingham University Hospitals NHS Trust, Nottingham, UK.
Rachael TaylorHealthcare for Older People, Nottingham University Hospitals NHS Trust, Nottingham, UK.
Denise KendrickDepartment of Medicine, University of Nottingham, Nottingham, UK.
Hannah CarpenterDepartment of Medicine, University of Nottingham, Nottingham, UK.
Steve IliffeDepartment of Primary Care & Population Health, University College London, London, UK.
Richard MorrisDepartment of Primary Care & Population Health, University College London, London, UK.
Heather GageSchool of Economics, University of Surrey, Guilford, UK.
Dawn A SkeltonSchool of Health and Life Sciences, Glasgow Caledonian University, Glasgow, UK.
Susie Dinan-YoungDepartment of Primary Care & Population Health, University College London, London, UK.
Katherine Brooke-WavellSchool of Sport, Exercise and Health Sciences, Loughborough University, Loughborough, UK.
University College London · GBNottingham University Hospitals NHS Trust · GBUniversity of Nottingham · GBDeakin University · AUGlasgow Caledonian University · GBLoughborough University · GBUniversity of Surrey · GB

Funding

Medical Research Council MR/K00414X/1
6 · The paper itself

Abstract

backgroundexercise can reduce osteoporotic fracture risk by strengthening bone or reducing fall risk. Falls prevention exercise programmes can reduce fall incidence, and also include strengthening exercises suggested to load bone, but there is little information as to whether these programmes influence bone mineral density (BMD) and strength.

objectiveto evaluate the skeletal effects of home (Otago Exercise Programme, OEP) and group (Falls Exercise Management, FaME) falls prevention exercise programmes relative to usual care in older people.

methodsmen and women aged over 65 years were recruited through primary care. They were randomised by practice to OEP, FaME or usual care. BMD, bone mineral content (BMC) and structural properties were measured in Nottingham site participants before and after the 24-week intervention.

resultsparticipants were 319 men and women, aged mean(SD) 72(5) years. Ninety-two percentage of participants completed the trial. The OEP group completed 58(43) min/week of home exercise, while the FaME group completed 39(16) and 30(24) min/week of group and home exercise, respectively. Femoral neck BMD changes did not differ between treatment arms: mean (95% CI) effect sizes in OEP and FaME relative to usual care arm were -0.003(-0.011,0.005) and -0.002(-0.010,0.005) g cm(-2), respectively; P = 0.44 and 0.53. There were no significant changes in BMD or BMC at other skeletal sites, or in structural parameters.

conclusionsfalls prevention exercise programmes did not influence BMD in older people. To increase bone strength, programmes may require exercise that exerts higher strains on bone or longer duration.

Indexed as

Absorptiometry, PhotonAccidental FallsAccidents, HomeAgedAge FactorsBone DensityExercise TherapyExercise ToleranceFemaleHumansIncidenceMaleOsteoporotic FracturesPrimary Health CareUnited Kingdomagedbone mineral densityexercisemenosteoporosispreventionprimary care, older peoplewomenX-ray absorptiometry

Identifiers

PMID25906791
PMCPMC4476850
OpenAlexW2101369563

What OpenQuestion holds

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Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.