ArticleGlobal health action2015
Cost and impact of scaling up interventions to save lives of mothers and children: taking South Africa closer to MDGs 4 and 5.
Article in Global health action, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 34 papers, 5 of them syntheses that pooled it.
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Who cites it
34 citing papers in PubMed, 5 syntheses or guidelines pooled it.
- Economic evaluations of scaling up strategies of evidence-based health interventions: a systematic review.BMC health services research · 2025Pooled it
- Economic Evaluations of Child Nutrition Interventions in Low- and Middle-Income Countries: Systematic Review and Quality Appraisal.Advances in nutrition (Bethesda, Md.) · 2022Pooled it
- The pooled estimate of the total fertility rate in sub-Saharan Africa using recent (2010-2018) Demographic and Health Survey data.Frontiers in public health · 2022Pooled it
- Knowledge and utilisation of preconception care and associated factors among women in Ethiopia: systematic review and meta-analysis.Reproductive health · 2021Pooled it
- Ending malnutrition in all its forms requires scaling up proven nutrition interventions and much more: a 129-country analysis.BMC medicine · 2020Pooled it
- Predicting under-five child mortality in Zambia: Machine learning versus parametric survival models.PloS one · 2026Article
- Article
- Pregnancy-Associated Acute Kidney Injury in Low-Resource Settings: Progress Over the Last Decade.Seminars in nephrology · 2022Review
- Determinants of contraceptive decision making among married women in Sub-Saharan Africa from the recent Demographic and Health Survey data.BMC women's health · 2022Article
- Leveraging microgrants to support capacity-building workshops in low- and middle-income countries for meeting the Sustainable Development Goals.Journal of the Medical Library Association : JMLA · 2022Article
- Article
- Patterns, trends, and factors associated with contraceptive use among adolescent girls in Zambia (1996 to 2014): a multilevel analysis.BMC women's health · 2020Article
- Article
- Communication between mothers and health workers is important for quality of newborn care: a qualitative study in neonatal units in district hospitals in South Africa.BMC pediatrics · 2019Observational
- How to improve the quality of care for women with postpartum haemorrhage at Onandjokwe Hospital, Namibia: quality improvement study.BMC pregnancy and childbirth · 2019Article
- Are there decision support tools that might strengthen the health system for perinatal care in South African district hospitals? A review of the literature.BMC health services research · 2019Review
- Utilization of preconception care and associated factors among reproductive age group women in Debre Birhan town, North Shewa, Ethiopia.Reproductive health · 2019Article
- The MomConnect Nurses and Midwives Support Platform (NurseConnect): A Qualitative Process Evaluation.JMIR mHealth and uHealth · 2019Article
- Effects of scaling up various community-level interventions on child mortality in Burundi, Kenya, Rwanda, Uganda and Tanzania: a modeling study.Global health research and policy · 2019Article
- Measurement approaches in continuum of care for maternal health: a critical interpretive synthesis of evidence from LMICs and its implications for the South African context.BMC health services research · 2018Review
Corrections and comments
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Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundSouth Africa has made substantial progress on child and maternal mortality, yet many avoidable deaths of mothers and children still occur. This analysis identifies priority interventions to be scaled up nationally and projects the potential maternal and child lives saved.
designWe modelled the impact of maternal, newborn and child interventions using the Lives Saved Tools Projections to 2015 and used realistic coverage increases based on expert opinion considering recent policy change, financial and resource inputs, and observed coverage change. A scenario analysis was undertaken to test the impact of increasing intervention coverage to 95%.
resultsBy 2015, with realistic coverage, the maternal mortality ratio (MMR) can reduce to 153 deaths per 100,000 and child mortality to 34 deaths per 1,000 live births. Fifteen interventions, including labour and delivery management, early HIV treatment in pregnancy, prevention of mother-to-child transmission and handwashing with soap, will save an additional 9,000 newborns and children and 1,000 mothers annually. An additional US$370 million (US$7 per capita) will be required annually to scale up these interventions. When intervention coverage is increased to 95%, breastfeeding promotion becomes the top intervention, the MMR reduces to 116 and the child mortality ratio to 23.
conclusionsThe 15 interventions identified were adopted by the National Department of Health, and the Health Minister launched a campaign to encourage Provincial Health Departments to scale up coverage. It is hoped that by focusing on implementing these 15 interventions at high quality, South Africa will reach Millennium Development Goal (MDG) 4 soon after 2015 and MDG 5 several years later. Focus on HIV and TB during early antenatal care is essential. Strategic gains could be realised by targeting vulnerable populations and districts with the worst health outcomes. The analysis demonstrates the usefulness of priority setting tools and the potential for evidence-based decision making in the health sector.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.