Evidence map›Paper›PMID 25906422›Full record

ReviewExercise and sport sciences reviews2015

Pathways Mediating Activity-Induced Enhancement of Recovery From Peripheral Nerve Injury.

Manning J Sabatier, Arthur W English

Abstract readReview
In one paragraph

Review in Exercise and sport sciences reviews, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Review
  8. Article
  9. Review
  10. Article
  11. Article
  12. Article
  13. Review
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  15. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Manning J Sabatier1Departments of Rehabilitation Medicine and 2Cell Biology, Emory University School of Medicine, Atlanta, GA.
Arthur W English

Funding

IRACDA Fellowships in Research and Science Training (FIRST)K12GM000680 · NIGMS · EMORY UNIVERSITY · PI BROWN, LOU ANN S, MCCARTY, NAEL A · 2000 to 2024
$41.2M
SPINAL CIRCUITS &THE MUSCULOSKELETAL SYSTEMP01HD032571 · NICHD · EMORY UNIVERSITY · PI GOOLSBY, WILLIAM · 1995 to 2016
$16.2M
Exercise, neurotrophins, and axon regeneration in the PNSR01NS057190 · NINDS · EMORY UNIVERSITY · PI ENGLISH, ARTHUR W. · 2007 to 2016
$3.3M
Proteoglycan degradation and functional recovery after peripheral nerve injuryR21HD053669 · NICHD · EMORY UNIVERSITY · PI ENGLISH, ARTHUR W · 2006 to 2007
$320k
NICHD NIH HHS HD032571NICHD NIH HHS HD053669NICHD NIH HHS P01 HD032571NICHD NIH HHS R21 HD053669NIGMS NIH HHS K12 GM000680NIGMS NIH HHS K12-GM00680-05NINDS NIH HHS R01 NS057190
6 · The paper itself

Abstract

This article outlines the novel hypothesis that exercise promotes axon regeneration after peripheral nerve injury through neuronal brain-derived neurotrophic factor (BDNF), and there are three required means of promoting BDNF expression: 1) increased signaling through androgen receptors, 2) increased cAMP-responsive element-binding protein expression, and 3) increased expression of the transcription factor SRY-box containing gene 11.

Indexed as

AnimalsAxonsBrain-Derived Neurotrophic FactorCyclic AMP Response Element-Binding ProteinHumansNerve RegenerationPeripheral Nerve InjuriesReceptors, AndrogenSignal TransductionSOXC Transcription FactorsBDNF protein, humanBrain-Derived Neurotrophic FactorCyclic AMP Response Element-Binding ProteinReceptors, AndrogenSox11 protein, mouseSOXC Transcription Factors

Identifiers

PMID25906422
PMCPMC4470799

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.