Evidence map›Paper›PMID 25906025›Full record

Observational studyNPJ primary care respiratory medicine2015

Exploring the impact of chronic obstructive pulmonary disease (COPD) on diabetes control in diabetes patients: a prospective observational study in general practice.

Hilde D Luijks, Wim J C de Grauw, Jacobus H J Bor, Chris van Weel, Antoine L M Lagro-Janssen, Marion C J Biermans, Tjard R Schermer

Open access · goldAbstract readObservational Study
PubMed Full text at PMC Publisher
In one paragraph

Observational study in NPJ primary care respiratory medicine, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed, 1 pooled it
1.3field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 1 synthesis or guideline pooled it, 9 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Observational
  4. Article
  5. Observational
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Hilde D LuijksDepartment of Primary and Community Care, Radboud university medical center, Nijmegen, The Netherlands.
Wim J C de GrauwDepartment of Primary and Community Care, Radboud university medical center, Nijmegen, The Netherlands.
Jacobus H J BorDepartment of Primary and Community Care, Radboud university medical center, Nijmegen, The Netherlands.
Chris van Weel1] Department of Primary and Community Care, Radboud university medical center, Nijmegen, The Netherlands [2] Australian Primary Health Care Research Institute, Australian National University, Canberra, ACT, Australia.
Antoine L M Lagro-JanssenDepartment of Primary and Community Care, Radboud university medical center, Nijmegen, The Netherlands.
Marion C J BiermansDepartment of Primary and Community Care, Radboud university medical center, Nijmegen, The Netherlands.
Tjard R SchermerDepartment of Primary and Community Care, Radboud university medical center, Nijmegen, The Netherlands.
Radboud University Medical Center · NLRadboud University Nijmegen · NL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundLittle is known about the association between COPD and diabetes control parameters.

aimsTo explore the association between comorbid COPD and longitudinal glycaemic control (HbA1C) and systolic blood pressure (SBP) in a primary care cohort of diabetes patients.

methodsThis is a prospective cohort study of type 2 diabetes patients in the Netherlands. In a mixed model analysis, we tested differences in the 5-year longitudinal development of HbA1C and SBP according to COPD comorbidity (present/absent). We corrected for relevant covariates. In subgroup effect analyses, we tested whether potential differences between diabetes patients with/without COPD were modified by age, sex, socio-economic status (SES) and body mass index (BMI).

resultsWe analysed 610 diabetes patients. A total of 63 patients (10.3%) had comorbid COPD. The presence of COPD was not significantly associated with the longitudinal development of HbA1C (P=0.54) or SBP (P=0.33), but subgroup effect analyses showed significant effect modification by SES (P<0.01) and BMI (P=0.03) on SBP. Diabetes patients without COPD had a flat SBP trend over time, with higher values in patients with a high BMI. For diabetes patients with COPD, SBP gradually increased over time in the middle- and high-SES groups, and it decreased over time in those in the low-SES group.

conclusionsThe longitudinal development of HbA1C was not significantly associated with comorbid COPD in diabetes patients. The course of SBP in diabetes patients with COPD is significantly associated with SES (not BMI) in contrast to those without COPD. Comorbid COPD was associated with longitudinal diabetes control parameters, but it has complex interactions with other patient characteristics. Further research is needed.

Indexed as

AgedBody Mass IndexComorbidityDiabetes Mellitus, Type 2FemaleGeneral PracticeGlycated HemoglobinHumansMaleMiddle AgedProspective StudiesPulmonary Disease, Chronic ObstructiveSocioeconomic FactorsGlycated Hemoglobin

Identifiers

PMID25906025
PMCPMC4532160
OpenAlexW2199326350

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.