Evidence map›Paper›PMID 25905811›Full record

ReviewNeuron2015

Glial Regulation of the Neuronal Connectome through Local and Long-Distant Communication.

R Douglas Fields, Dong Ho Woo, Peter J Basser

Abstract readReview
In one paragraph

Review in Neuron, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 89 papers.

0numbers the graph read from it
0cells of the map it votes in
89citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

89 citing papers in PubMed.

  1. Trial
  2. Measuring conduction velocity distributions in peripheral nerves using neurophysiological techniques.Clinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology · 2020
    Trial
  3. Review
  4. Review
  5. Review
  6. Article
  7. Article
  8. Smart Nanotechnologies for Multimodal Neuromodulation and Brain Interfacing.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026
    Review
  9. Article
  10. Review
  11. Review
  12. Article
  13. Article
  14. Article
  15. Modeling traveling calcium waves in cellular structures.Journal of computational neuroscience · 2025
    Article
  16. Article
  17. Article
  18. Article
  19. Article
  20. Article

29 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

R Douglas FieldsNervous System Development and Plasticity Section, The Eunice Kennedy Shriver National Institute of Child Health and Human Development, Bethesda, MD 20892, USA. Electronic address: fieldsd@mail.nih.gov.
Dong Ho WooNervous System Development and Plasticity Section, The Eunice Kennedy Shriver National Institute of Child Health and Human Development, Bethesda, MD 20892, USA.
Peter J BasserSection on Tissue Biophysics and Biomimetics, Program on Pediatric Imaging and Tissue Sciences, The Eunice Kennedy Shriver National Institute of Child Health and Human Development, NIH, Bethesda, MD 20892, USA.

Funding

Nervous System Development and PlasticityZIAHD000713 · NICHD · EUNICE KENNEDY SHRIVER NATIONAL INSTITUTE OF CHILD HEALTH & HUMAN DEVELOPMENT · PI FIELDS, RICHARD DOUGLAS · 2009 to 2023
$17.7M
Physical-chemical Aspects Of Cell And Tissue ExcitabilityZIAHD000268 · NICHD · EUNICE KENNEDY SHRIVER NATIONAL INSTITUTE OF CHILD HEALTH & HUMAN DEVELOPMENT · PI BASSER, PETER J. · 2009 to 2017
$796k
Intramural NIH HHS ZIA HD000713
6 · The paper itself

Abstract

If "the connectome" represents a complete map of anatomical and functional connectivity in the brain, it should also include glia. Glia define and regulate both the brain's anatomical and functional connectivity over a broad range of length scales, spanning the whole brain to subcellular domains of synaptic interactions. This Perspective article examines glial interactions with the neuronal connectome (including long-range networks, local circuits, and individual synaptic connections) and highlights opportunities for future research. Our understanding of the structure and function of the neuronal connectome would be incomplete without an understanding of how all types of glia contribute to neuronal connectivity and function, from single synapses to circuits.

Indexed as

ConnectomeAnimalsAstrocytesHumansMiceNerve Fibers, MyelinatedNerve NetNeural ConductionNeurogliaOptic NerveSynapsesSynaptic Transmission

Identifiers

PMID25905811
PMCPMC4426493

What OpenQuestion holds

Textmetadata
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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.