ArticlePloS one2015
Antibiotic Prescription for COPD Exacerbations Admitted to Hospital: European COPD Audit.
Article in PloS one, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers, 2 of them syntheses that pooled it.
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Who cites it
30 citing papers in PubMed, 2 syntheses or guidelines pooled it, 56 citations in OpenAlex.
- A systematic review and Bayesian meta-analysis of the antibiotic treatment courses in AECOPD.Frontiers in pharmacology · 2023Pooled it
- Procalcitonin to guide antibiotic administration in COPD exacerbations: a meta-analysis.European respiratory review : an official journal of the European Respiratory Society · 2017Pooled it
- 2-Day versus C-reactive protein guided antibiotherapy with levofloxacin in acute COPD exacerbation: A randomized controlled trial.PloS one · 2021Trial
- Quality of antibiotics prescription in hospitals in Burkina Faso: a multispecialty clinical audit.Antimicrobial resistance and infection control · 2026Article
- Article
- The use of antibiotics in the early stage of acute exacerbation of chronic obstructive pulmonary disease in patients without obvious signs of infection: a multicenter, randomized, parallel-controlled study.Frontiers in pharmacology · 2024Article
- Antimicrobial stewardship in primary health care programs in humanitarian settings: the time to act is now.Antimicrobial resistance and infection control · 2023Article
- Time-Updated Phenotypic Guidance of Corticosteroids and Antibiotics in COPD: Rationale, Perspective and a Proposed Method.Biomedicines · 2023Review
- In-hospital antibiotic use for severe chronic obstructive pulmonary disease exacerbations: a retrospective observational study.BMC pulmonary medicine · 2023Observational
- Clinical Management of COPD in the Real World: Can Studies Reveal Errors in Management and Pathways to Improve Patient Care?Pragmatic and observational research · 2023Review
- Antibiotics Use among Patients with Acute Exacerbation of Chronic Obstructive Pulmonary Disease in the Department of Internal Medicine of a Tertiary Care Centre: A Descriptive Cross-sectional Study.JNMA; journal of the Nepal Medical Association · 2022Article
- Eosinopenia as a biomarker for antibiotic use in COPD exacerbations: protocol for a retrospective hospital-based cohort study.BMJ open · 2022Article
- Procalcitonin-guided initiation of antibiotics in AECOPD inpatients: study protocol for a multicenter randomised controlled trial.BMJ open · 2021Article
- Patient's treatment burden related to care coordination in the field of respiratory diseases.Breathe (Sheffield, England) · 2021Review
- Development and Relevance of Hypercapnia in COPD.Canadian respiratory journal · 2021Article
- Management of acute COPD exacerbations in Australia: do we follow the guidelines?ERJ open research · 2020Article
- Was the implementation strategy of the ProACT trial adequately proactive?Breathe (Sheffield, England) · 2019Article
- Effects of air pollution on acute exacerbation of chronic obstructive pulmonary disease: a descriptive retrospective study (pol-AECOPD).International journal of chronic obstructive pulmonary disease · 2019Article
- Comparative Effectiveness Of Fluoroquinolone Antibiotic Use In Uncomplicated Acute Exacerbations Of COPD: A Multi-Cohort Study.International journal of chronic obstructive pulmonary disease · 2019Article
- Antibiotics for COPD exacerbations: does drug or duration matter? A primary care database analysis.BMJ open respiratory research · 2019Article
Corrections and comments
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Authors and funding
5 authors at 4 institutions in 3 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveAppropriate use of antibiotics in the management of hospitalised patients with COPD exacerbations is defined within the GOLD strategy. This paper analyses the factors associated with antibiotic prescribing in patients to better understand how prescribing may be improved.
methodsThe European COPD audit was a study of clinical care in 384 hospitals from 13 European countries between 2010 and 2011 enrolling 16018 patients. Those admitted to hospital due to a clinician-made diagnosis of exacerbation of COPD at the time of discharge were audited. We defined antibiotic prescribing compliance as consistent with the GOLD 2010 recommendations. Two different multivariate models were used to evaluate factors associated with the prescription of antibiotics and the guideline-compliant prescriptions.
resultsOverall 86% of admissions were given antibiotics but only 61.4% cases met the GOLD recommendations. Antibiotics were more likely to be given in hospital and at discharge if received prior to admission. Antibiotic prescription was more likely in patients who met the GOLD recommendations and in those with radiological consolidation but there was also a significant use of antibiotics in patients who did not meet either criterion. Patients cared for on a Respiratory Ward were more likely to receive GOLD compliant antibiotic management.
conclusionsThe present study describes the audited in-hospital antibiotic prescription for COPD exacerbation across different European countries. In general, there is an apparent overuse of antibiotics likely to be associated with both patient and practice-related variables.
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