ReviewClinical and translational allergy2014
Role of the skin microbiome in atopic dermatitis.
Review in Clinical and translational allergy, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
29 citing papers in PubMed, 1 synthesis or guideline pooled it, 97 citations in OpenAlex.
- Mud therapy and skin microbiome: a review.International journal of biometeorology · 2018Pooled it
- Topical probioticFrontiers in medicine · 2026Trial
- Prospective, comparative clinical pilot study of cold atmospheric plasma device in the treatment of atopic dermatitis.Scientific reports · 2021Trial
- The Women's Microbiome: Molecular Insights, Clinical Gaps, and Future Frontiers in Precision Health with Implications for Gulf Cooperation Council Populations.International journal of molecular sciences · 2026Review
- Skin and gut microbiome in atopic dermatitis: Mechanisms and therapeutic opportunities.Pediatric allergy and immunology : official publication of the European Society of Pediatric Allergy and Immunology · 2025Review
- Atopic dermatitis, primary atopic disorders, and the cutaneous microbiome: current understanding of an expanding field.Frontiers in pediatrics · 2025Review
- Study on the molecular mechanism of atopic dermatitis in mice based on skin and serum metabolomic analysis.Metabolomics : Official journal of the Metabolomic Society · 2024Article
- Understanding and treating diabetic foot ulcers: Insights into the role of cutaneous microbiota and innovative therapies.Skin health and disease · 2024Review
- Antioxidant, Antibacterial Properties of Novel Peptide CP by Enzymatic Hydrolysis ofMarine drugs · 2024Article
- Characterization of the skin microbiota in bullous pemphigoid patients and controls reveals novel microbial indicators of disease.Journal of advanced research · 2023Article
- Staphylococcus epidermidis and its dual lifestyle in skin health and infection.Nature reviews. Microbiology · 2023Review
- Microbiome and Human Health: Current Understanding, Engineering, and Enabling Technologies.Chemical reviews · 2023Review
- Controlling skin microbiome as a new bacteriotherapy for inflammatory skin diseases.Inflammation and regeneration · 2022Review
- The Skin Microbiome in Cutaneous T-Cell Lymphomas (CTCL)-A Narrative Review.Pathogens (Basel, Switzerland) · 2022Review
- The Role of Early Life Microbiota Composition in the Development of Allergic Diseases.Microorganisms · 2022Review
- Gene Expression Profile Analyses of the Skin Response of Balb/c-Nu Mice Model Injected byClinical, cosmetic and investigational dermatology · 2022Article
- Comparison of Gut Viral Communities in Atopic Dermatitis and Healthy Children.Frontiers in medicine · 2022Article
- Prevalence of Skin Reactions and Self-Reported Allergies in 5 Countries with Their Social Impact Measured through Quality of Life Impairment.International journal of environmental research and public health · 2021Article
- Comparative Analysis of the Microbiome across the Gut-Skin Axis in Atopic Dermatitis.International journal of molecular sciences · 2021Review
- Diagnostic Models for Atopic Dermatitis Based on Serum Microbial Extracellular Vesicle Metagenomic Analysis: A Pilot Study.Allergy, asthma & immunology research · 2020Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Atopic dermatitis (AD) is a common inflammatory skin disorder and characterized by abnormalities in both skin barrier structures and alternations of the immune response. Molecular genetics have dramatically changed our vision of the micro-organisms colonizing the human skin and recently well-documented changes in the skin microbiome in atopic dermatitis have become evident. The microbiome shifts have been primarily documented during disease flares and localized to sites of disease predilection, e.g. folds or facial area. In contrast, active treatment has been associated with a recolonisation and higher cutaneous microbial diversity. Additionally to the known dysfunctions in barrier function of the skin (e.g. filaggrin mutations) and immunologic disturbances (e.g. Th2-shift), evidence is rising that atopic dermatitis is also connected to a dysbiosis of the microbial community without an invading pathogen. In the future the investigation of the patient's skin microbiome may have a foothold in the clinician's diagnostic repertoire and treatment of atopic dermatitis.
Indexed as
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.