Evidence map›Paper›PMID 25904872›Full record

ArticleFrontiers in psychiatry2015

Musical hallucinations treated with acetylcholinesterase inhibitors.

Jan Dirk Blom, Jan Adriaan F Coebergh, René Lauw, Iris E C Sommer

Open access · goldAbstract read
In one paragraph

Article in Frontiers in psychiatry, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed, 1 pooled it
1.8field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 1 synthesis or guideline pooled it, 30 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Review
  6. Article
  7. Article
  8. Article
  9. Musical Hallucination Caused by Ceftazidime in a Woman with a Hearing Impairment.Clinical psychopharmacology and neuroscience : the official scientific journal of the Korean College of Neuropsychopharmacology · 2019
    Article
  10. Article
  11. Article
  12. Review
  13. Hearing and dementia.Journal of neurology · 2016
    Review
  14. Article
  15. Review
  16. Article
  17. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 2 countries.

Jan Dirk BlomParnassia Psychiatric Institute , The Hague , Netherlands ; Department of Psychiatry, University of Groningen , Groningen , Netherlands.
Jan Adriaan F CoeberghDepartment of Neurology, Ashford and St. Peter's Hospitals , Chertsey , UK ; Department of Neurology, St. George's Hospital , London , UK.
René LauwParnassia Psychiatric Institute , The Hague , Netherlands.
Iris E C SommerDepartment of Psychiatry, University Medical Center Utrecht , Utrecht , Netherlands ; Rudolf Magnus Institute of Neuroscience , Utrecht , Netherlands.
Parnassia Groep · NLSt George's Hospital · GBUniversity Medical Center Utrecht · NL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Musical hallucinations are relatively rare auditory percepts which, due to their intrusive nature and the accompanying fear of impending mental decline, tend to cause significant distress and impairment. Although their etiology and pathophysiology appear to be heterogeneous and no evidence-based treatment methods are available, case reports indicate that acetylcholinesterase inhibitors may yield positive results in patients with comorbid hearing loss. We present two female patients (aged 76 and 78 years) both of whom suffered from hearing impairment and practically incessant musical hallucinations. Both patients were successfully treated with the acetylcholinesterase inhibitor rivastigmine. Based on these two case descriptions and an overview of studies describing the use of acetylcholinesterase inhibitors in similar patients, we discuss possible mechanisms and propose further research on the use of acetylcholinesterase inhibitors for musical hallucinations experienced in concordance with hearing loss.

Indexed as

auditory Charles Bonnet syndromecholinergic systemdeafferentiationdonepezilhearing lossOliver Sacks’ syndromerelease hallucinationrivastigmine

Identifiers

PMID25904872
PMCPMC4387860
OpenAlexW1967608649

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.