ArticleThe Journal of neuroscience : the official journal of the Society for Neuroscience2015
Odor-taste convergence in the nucleus of the solitary tract of the awake freely licking rat.
Article in The Journal of neuroscience : the official journal of the Society for Neuroscience, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers, 1 of them a synthesis that pooled it.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
30 citing papers in PubMed, 1 synthesis or guideline pooled it.
- A Systematic Review of Direct Outputs from the Cerebellum to the Brainstem and Diencephalon in Mammals.Cerebellum (London, England) · 2024Pooled it
- Multisensory Integration Underlies the Distinct Representation of Odor-Taste Mixtures in the Gustatory Cortex of Behaving Rats.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2024Article
- Electrophysiological responses to appetitive and consummatory behavior in the rostral nucleus tractus solitarius in awake, unrestrained rats.bioRxiv : the preprint server for biology · 2024Article
- The effect of multisensory context and experience on flavor preference decisions in rats.Physiology & behavior · 2024Article
- Electrophysiological responses to appetitive and consummatory behavior in the rostral nucleus tractus solitarius in awake, unrestrained rats.Frontiers in integrative neuroscience · 2024Article
- The integrative process promoted by EMDR in dissociative disorders: neurobiological mechanisms, psychometric tools, and intervention efficacy on the psychological impact of the COVID-19 pandemic.Frontiers in psychology · 2023Review
- Multisensory integration of orally-sourced gustatory and olfactory inputs to the posterior piriform cortex in awake rats.The Journal of physiology · 2023Article
- COVID-19 Smell Impairment and Crosstalk with Hypoxia Physiology.Life (Basel, Switzerland) · 2022Article
- Characterization of Retronasal Airflow Patterns during Intraoral Fluid Discrimination Using a Low-Cost, Open-Source Biosensing Platform.Sensors (Basel, Switzerland) · 2022Article
- Neural processing and perception of Schroeder-phase harmonic tone complexes in the gerbil: Relating single-unit neurophysiology to behavior.The European journal of neuroscience · 2022Article
- Item Reduction, Psychometric and Biometric Properties of the Italian Version of the Body Perception Questionnaire-Short Form (BPQ-SF): The BPQ-22.International journal of environmental research and public health · 2021Article
- Against gustotopic representation in the human brain: There is no Cartesian Restaurant.Current opinion in physiology · 2021Article
- Neural Coding of Food Is a Multisensory, Sensorimotor Function.Nutrients · 2021Review
- Enhancing GABAergic Tone in the Rostral Nucleus of the Solitary Tract Reconfigures Sensorimotor Neural Activity.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2021Article
- Choice-dependent cross-modal interaction in the medial prefrontal cortex of rats.Molecular brain · 2021Article
- Cortical Hub for Flavor Sensation in Rodents.Frontiers in systems neuroscience · 2021Review
- Taste coding strategies in insular cortex.Experimental biology and medicine (Maywood, N.J.) · 2020Review
- Smell and Taste in Severe CoViD-19: Self-Reported vs. Testing.Frontiers in medicine · 2020Article
- Recognizing Taste: Coding Patterns Along the Neural Axis in Mammals.Chemical senses · 2019Review
- Heterogeneity of neuronal responses in the nucleus of the solitary tract suggests sensorimotor integration in the neural code for taste.Journal of neurophysiology · 2019Article
Corrections and comments
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Authors and funding
3 authors.
Funding
Abstract
Flavor is produced by the integration of taste, olfaction, texture, and temperature, currently thought to occur in the cortex. However, previous work has shown that brainstem taste-related nuclei also respond to multisensory inputs. Here, we test the hypothesis that taste and olfaction interact in the nucleus of the solitary tract (NTS; the first neural relay in the central gustatory pathway) in awake, freely licking rats. Electrophysiological recordings of taste and taste + odor responses were conducted in an experimental chamber following surgical electrode implantation and recovery. Tastants (0.1 m NaCl, 0.1 m sucrose, 0.01 m citric acid, and 0.0001 m quinine) were delivered for five consecutive licks interspersed with five licks of artificial saliva rinse delivered on a VR5 schedule. Odorants were n-amyl acetate (banana), acetic acid (vinegar), octanoic acid (rancid), and phenylethyl alcohol (floral). For each cell, metric space analyses were used to quantify the information conveyed by spike count, by the rate envelope, and by individual spike timing. Results revealed diverse effects of odorants on taste-response magnitude and latency across cells. Importantly, NTS cells were more competent at discriminating taste + odor stimuli versus tastants presented alone for all taste qualities using both rate and temporal coding. The strong interaction of odorants and tastants at the NTS underscores its role as the initial node in the neural circuit that controls food identification and ingestion.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.