Trial reportThe Journal of neuroscience : the official journal of the Society for Neuroscience2015
Cognitive training enhances intrinsic brain connectivity in childhood.
Trial report in The Journal of neuroscience : the official journal of the Society for Neuroscience, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 56 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
56 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Interventions with an Impact on Cognitive Functions in Cerebral Palsy: a Systematic Review.Neuropsychology review · 2023Pooled it
- The cognitive remediation of attention in HIV-associated neurocognitive disorders (HAND): A meta-analysis and systematic review.F1000Research · 2023Pooled it
- A digital intervention to support childhood cognition after the COVID-19 pandemic: a pilot trial.Scientific reports · 2024Trial
- Working memory training restores aberrant brain activity in adult attention-deficit hyperactivity disorder.Human brain mapping · 2020Trial
- The academic outcomes of working memory and metacognitive strategy training in children: A double-blind randomized controlled trial.Developmental science · 2020Trial
- Working memory training and brain structure and function in extremely preterm or extremely low birth weight children.Human brain mapping · 2020Trial
- Training-induced white matter microstructure changes in survivors of neonatal critical illness: A randomized controlled trial.Developmental cognitive neuroscience · 2019Trial
- Neuropsychological benefits of computerized cognitive rehabilitation training in Ugandan children surviving severe malaria: A randomized controlled trial.Brain research bulletin · 2019Trial
- Long-term far-transfer effects of working memory training in children with ADHD: a randomized controlled trial.European child & adolescent psychiatry · 2016Trial
- Does working memory training in children need to be adaptive? A randomized controlled trial.Child developmentTrial
- Intensive task-switching training and single-task training differentially affect behavioral and neural manifestations of cognitive control in children.Cerebral cortex (New York, N.Y. : 1991) · 2025Article
- Cross brain reshaping in congenital visual or hearing impairment: triple-network dysfunction.Brain communications · 2025Article
- Heterogenous brain activations across individuals localize to a common network.Communications biology · 2024Article
- Benefits of Playing at School: Filler Board Games Improve Visuospatial Memory and Mathematical Skills.Brain sciences · 2024Article
- Clinical Potential of Transcranial Focused Ultrasound for Neurorehabilitation in Pediatric Cancer Survivors.Brain sciences · 2024Review
- Strengthening of alpha synchronization is a neural correlate of cognitive transfer.Cerebral cortex (New York, N.Y. : 1991) · 2024Article
- Resting-state functional connectivity in children cooled for neonatal encephalopathy.Brain communications · 2024Article
- Working Memory Training for Children Using the Adaptive, Self-Select, and Stepwise Approaches to Setting the Difficulty Level of Training Activities: Protocol for a Randomized Controlled Trial.JMIR research protocols · 2023Article
- Mnemonic-trained brain tuning to a regular odd-even pattern subserves digit memory in children.NPJ science of learning · 2023Article
- Increased Striatal Presynaptic Dopamine in a Nonhuman Primate Model of Maternal Immune Activation: A Longitudinal Neurodevelopmental Positron Emission Tomography Study With Implications for Schizophrenia.Biological psychiatry. Cognitive neuroscience and neuroimaging · 2023Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
Abstract
In human participants, the intensive practice of particular cognitive activities can induce sustained improvements in cognitive performance, which in some cases transfer to benefits on untrained activities. Despite the growing body of research examining the behavioral effects of cognitive training in children, no studies have explored directly the neural basis of these training effects in a systematic, controlled fashion. Therefore, the impact of training on brain neurophysiology in childhood, and the mechanisms by which benefits may be achieved, are unknown. Here, we apply new methods to examine dynamic neurophysiological connectivity in the context of a randomized trial of adaptive working memory training undertaken in children. After training, connectivity between frontoparietal networks and both lateral occipital complex and inferior temporal cortex was altered. Furthermore, improvements in working memory after training were associated with increased strength of neural connectivity at rest, with the magnitude of these specific neurophysiological changes being mirrored by individual gains in untrained working memory performance.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.