ArticlePeritoneal dialysis international : journal of the International Society for Peritoneal Dialysis
Anterior ischemic optical neuropathy in children on chronic peritoneal dialysis: report of 7 cases.
Article in Peritoneal dialysis international : journal of the International Society for Peritoneal Dialysis. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
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Who cites it
8 citing papers in PubMed, 25 citations in OpenAlex.
- Non-infectious complications of peritoneal dialysis in children.Pediatric nephrology (Berlin, Germany) · 2025Review
- Anterior and posterior ischemic optic neuropathy in a child with focal segmental glomerulosclerosis on hemodialysis.Pediatric nephrology (Berlin, Germany) · 2024Article
- Bioimpedance analysis in children on peritoneal dialysis: to fill or not to fill?Pediatric nephrology (Berlin, Germany) · 2024Article
- Non-arteritic anterior ischemic optic neuropathy combined with branch retinal vein obstruction: A case report.World journal of clinical cases · 2023Article
- Acute bilateral vision loss in a toddler with stage 5 chronic kidney disease: Answers.Pediatric nephrology (Berlin, Germany) · 2021Article
- Anterior Ischemic Optic Neuropathy in a Child Receiving Chronic Hemodialysis.Case reports in nephrology · 2020Article
- Visual Impairment After Haemodialysis.Neuro-ophthalmology (Aeolus Press) · 2019Article
- Peritoneal dialysis in infants: never lose sight of-and from-arterial hypotension!Peritoneal dialysis international : journal of the International Society for Peritoneal DialysisArticle
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11 authors at 5 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundAnterior ischemic optic neuropathy (AION) is characterized by infarction of the optic nerve head due to hypoperfusion of the posterior ciliary arteries and causes sudden blindness in adults on chronic dialysis, but has rarely been described in children. Unlike adults, children do not have comorbidities related to aging.
methodsWe retrospectively analyzed data of 7 children on nocturnal continuous cycling peritoneal dialysis (CCPD) who developed AION identified within the Italian Registry of Pediatric Chronic Dialysis. We also summarized data from 10 cases reported in the literature.
resultsOur 7 patients suffered from acute onset bilateral blindness. Their mean age was 3.2 years and chronic hypotension had been observed prior the AION in 3 of the 7 children. Low systolic blood pressure (SBP) was associated with higher risk of developing AION according to statistical analysis. None recovered completely. In total, 11 out of 16 experienced a partial recovery and no clear evidence emerged favoring specific treatments.
conclusionsHypotensive children treated with CCPD are at increased risk of developing AION, which often results in irreversible blindness.
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