Evidence map›Paper›PMID 25904632›Full record

ArticleNucleic acids research2015

RSAT 2015: Regulatory Sequence Analysis Tools.

Alejandra Medina-Rivera, Matthieu Defrance, Olivier Sand, Carl Herrmann, Jaime A Castro-Mondragon, Jeremy Delerce, Sébastien Jaeger, Christophe Blanchet, Pierre Vincens, Christophe Caron and 8 more

Open access · goldAbstract read
In one paragraph

Article in Nucleic acids research, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 155 papers.

0numbers the graph read from it
0cells of the map it votes in
155citing papers in PubMed
23.5field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

155 citing papers in PubMed, 254 citations in OpenAlex.

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  16. Regulatory Evolution of theJournal of bacteriology · 2022
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  19. A novel SCARECROW-LIKE3 transcription factorPhysiology and molecular biology of plants : an international journal of functional plant biology · 2022
    Article
  20. Article

95 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

18 authors at 5 institutions in 4 countries.

Alejandra Medina-RiveraGenetics and Genome Biology Program, SickKids Research Institute, Toronto, Canada.
Matthieu DefranceLaboratory of Cancer Epigenetics, Université Libre de Bruxelles, Route de Lennik 808, 1070 Brussels, Belgium.
Olivier SandCNRS-UMR8199 Institut de Biologie de Lille, Génomique Intégrative et Modélisation des Maladies Métaboliques, 1, rue du Pr Calmette, 59000 Lille, France European Genomic Institute for Diabetes (EGID), F-3508, 59000 Lille, France.
Carl HerrmannUMR_S 1090 TAGC, INSERM, Marseille, France; Aix-Marseille Université, Marseille, France Institute of Pharmacy and Molecular Biotechnology, and Bioquant Center, University of Heidelberg, Im Neuenheimer Feld 267, Heidelberg 69120, Germany Division of Theoretical Bioinformatics, German Cancer Research Center (DKFZ), Im Neuenheimer Feld 280, Heidelberg 69120, Germany.
Jaime A Castro-MondragonUMR_S 1090 TAGC, INSERM, Marseille, France; Aix-Marseille Université, Marseille, France.
Jeremy DelerceUMR_S 1090 TAGC, INSERM, Marseille, France; Aix-Marseille Université, Marseille, France.
Sébastien JaegerCentre d'Immunologie de Marseille-Luminy (CIML), Aix-Marseille University, UM2, Marseille, France Institut National de la Santé et de la Recherche Médicale (Inserm), U1104, Marseille, France Centre National de la Recherche Scientifique (CNRS), UMR7280, Marseille, France.
Christophe BlanchetCNRS, UMS 3601, Institut Français de Bioinformatique, IFB-core, Avenue de la Terrasse, F-91190 Gif-sur-Yvette, France.
Pierre VincensEcole Normale Supérieure, Institut de Biologie de l'ENS, IBENS, Paris, F-75005, France Inserm, U1024, Paris, F-75005, France CNRS, UMR 8197, Paris, F-75005, France.
Christophe CaronStation Biologique/Service Informatique et Bio-informatique, Place Georges Teissier - CS 90074, 29688 Roscoff Cedex, France.
Daniel M StainesEuropean Molecular Biology Laboratory, European Bioinformatics Institute (EMBL-EBI), Wellcome Trust Genome Campus, Hinxton, Cambridge CB10 1SD, UK.
Bruno Contreras-MoreiraEstación Experimental de Aula Dei/CSIC, Av. Montañana 1.005, 50059 Zaragoza, Spain Fundación ARAID, calle María de Luna 11, 50018 Zaragoza, Spain.
Marie ArtufelUMR_S 1090 TAGC, INSERM, Marseille, France; Aix-Marseille Université, Marseille, France.
Lucie Charbonnier-KhamvongsaUMR_S 1090 TAGC, INSERM, Marseille, France; Aix-Marseille Université, Marseille, France.
Céline HernandezEcole Normale Supérieure, Institut de Biologie de l'ENS, IBENS, Paris, F-75005, France Inserm, U1024, Paris, F-75005, France CNRS, UMR 8197, Paris, F-75005, France.
Denis ThieffryEcole Normale Supérieure, Institut de Biologie de l'ENS, IBENS, Paris, F-75005, France Inserm, U1024, Paris, F-75005, France CNRS, UMR 8197, Paris, F-75005, France.
Morgane Thomas-ChollierEcole Normale Supérieure, Institut de Biologie de l'ENS, IBENS, Paris, F-75005, France Inserm, U1024, Paris, F-75005, France CNRS, UMR 8197, Paris, F-75005, France mthomas@biologie.ens.fr.
Jacques van HeldenEuropean Genomic Institute for Diabetes (EGID), F-3508, 59000 Lille, France Laboratoire de Bioinformatique des Génomes et des Réseaux (BiGRe), Université Libre de Bruxelles, Campus Plaine, CP 263, Bld du Triomphe, B-1050 Bruxelles, Belgium Jacques.van-Helden@univ-amu.fr.
Inserm · FRAix-Marseille Université · FRGerman Cancer Research Center · DESickKids Foundation · CAWellcome Trust · GB

Funding

Canadian Institutes of Health Research GET-101831
6 · The paper itself

Abstract

RSAT (Regulatory Sequence Analysis Tools) is a modular software suite for the analysis of cis-regulatory elements in genome sequences. Its main applications are (i) motif discovery, appropriate to genome-wide data sets like ChIP-seq, (ii) transcription factor binding motif analysis (quality assessment, comparisons and clustering), (iii) comparative genomics and (iv) analysis of regulatory variations. Nine new programs have been added to the 43 described in the 2011 NAR Web Software Issue, including a tool to extract sequences from a list of coordinates (fetch-sequences from UCSC), novel programs dedicated to the analysis of regulatory variants from GWAS or population genomics (retrieve-variation-seq and variation-scan), a program to cluster motifs and visualize the similarities as trees (matrix-clustering). To deal with the drastic increase of sequenced genomes, RSAT public sites have been reorganized into taxon-specific servers. The suite is well-documented with tutorials and published protocols. The software suite is available through Web sites, SOAP/WSDL Web services, virtual machines and stand-alone programs at http://www.rsat.eu/.

Indexed as

Regulatory Elements, TranscriptionalSoftwareBinding SitesGenetic VariationGenomicsHumansInternetNucleotide MotifsTranscription FactorsTranscription Factors

Identifiers

PMID25904632
PMCPMC4489296
OpenAlexW2096629558

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.