Evidence map›Paper›PMID 25904201›Full record

ArticleJournal of autism and developmental disorders2015

Autism Symptomatology in Boys with Fragile X Syndrome: A Cross Sectional Developmental Trajectories Comparison with Nonsyndromic Autism Spectrum Disorder.

Angela John Thurman, Andrea McDuffie, Sara T Kover, Randi J Hagerman, Leonard Abbeduto

Open access · greenAbstract read
In one paragraph

Article in Journal of autism and developmental disorders, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 40 papers.

0numbers the graph read from it
0cells of the map it votes in
40citing papers in PubMed
3.1field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

40 citing papers in PubMed, 51 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Adaptive, behavioral, and cognitive outcomes in individuals with fragile X syndrome with varying autism severity.International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience · 2023
    Article
  8. Article
  9. Targeted Treatments for Fragile X Syndrome.Advances in neurobiology · 2023
    Article
  10. Review
  11. Article
  12. Working Memory Training in Youth With Autism, Fragile X, and Intellectual Disability: A Pilot Study.American journal on intellectual and developmental disabilities · 2022
    Article
  13. Article
  14. Article
  15. Article
  16. Daily Living Skills in Adolescent and Young Adult Males With Fragile X Syndrome.American journal on intellectual and developmental disabilities · 2022
    Article
  17. Article
  18. Article
  19. The Phenotypic Profile Associated With theFrontiers in psychiatry · 2021
    Article
  20. Language Development From Early Childhood to Adolescence in Youths With Fragile X Syndrome.Journal of speech, language, and hearing research : JSLHR · 2020
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Angela John ThurmanMIND Institute, University of California Davis, 2825 50th Street, Room 2101, Sacramento, CA, 95817, USA, ajthurman@ucdavis.edu.
Andrea McDuffie
Sara T Kover
Randi J Hagerman
Leonard Abbeduto
University of California, Davis · USUniversity of Washington · US

Funding

Rodent Behavior CoreU54HD079125 · NICHD · UNIVERSITY OF CALIFORNIA AT DAVIS · PI HERTZ-PICCIOTTO, IRVA · 2013 to 2019
$8.5M
Social-Affective Bases of Word Learning in Fragile X Syndrome and AutismR01HD054764 · NICHD · UNIVERSITY OF WISCONSIN-MADISON · PI ABBEDUTO, LEONARD J. · 2008 to 2012
$2.9M
NICHD NIH HHS R01 HD054764NICHD NIH HHS U54 HD079125
6 · The paper itself

Abstract

Although males with fragile X syndrome (FXS) are frequently described as demonstrating autism symptomatology, there is much debate regarding whether the behavioral symptoms representing the core domains of autism are the result of the same or different underlying neurological/psychological mechanisms. The present study used a cross-sectional developmental trajectories approach to compare the profiles of autism symptomatology relative to chronological age (CA), nonverbal IQ, and expressive vocabulary ability between individuals with FXS and individuals with nonsyndromic ASD. Results suggest that the onset of autism symptoms and their developmental trajectories in males with FXS differ in important ways as a function of CA, nonverbal cognitive ability, and expressive vocabulary relative to males with nonsyndromic ASD. Theoretical and clinical implications are discussed.

Indexed as

AdolescentAutistic DisorderFragile X SyndromeHumansLanguage DevelopmentMale

Identifiers

PMID25904201
PMCPMC4554893
OpenAlexW2065504304

What OpenQuestion holds

Textmetadata
LicenceTDM
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.