ArticleJournal of aging and health2015
Childhood Adversities and Adult Cardiometabolic Health: Does the Quantity, Timing, and Type of Adversity Matter?
Article in Journal of aging and health, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 79 papers, 7 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
79 citing papers in PubMed, 7 syntheses or guidelines pooled it, 140 citations in OpenAlex.
- Dimensions of early life adversity and cardiometabolic health in adulthood: A systematic review and meta-analysis.Health psychology : official journal of the Division of Health Psychology, American Psychological Association · 2026Pooled it
- Adverse childhood experiences and cognitive outcomes among older adults in low-income and middle-income countries: a systematic review.BMJ open · 2026Pooled it
- Measuring adversity in the ABCD® Study: systematic review and recommendations for best practices.BMC medical research methodology · 2025Pooled it
- Adverse childhood experiences and risk of diabetes: A systematic review and meta-analysis.Journal of global health · 2022Pooled it
- Status of injuries as a public health burden among children and adolescents in China: A systematic review and meta-analysis.Medicine · 2019Pooled it
- Life course health consequences and associated annual costs of adverse childhood experiences across Europe and North America: a systematic review and meta-analysis.The Lancet. Public health · 2019Pooled it
- Cumulative childhood adversity and adult cardiometabolic disease: A meta-analysis.Health psychology : official journal of the Division of Health Psychology, American Psychological Association · 2018Pooled it
- Using insertable cardiac monitors to test determinants of heart rate and activity in captive baboons.Animal biotelemetry · 2026Article
- Women's Help-Seeking and Service Experiences: Sexual Revictimization in Regional and Rural Areas.Violence against women · 2026Article
- Associations between adverse childhood experiences and cardiometabolic health in later adulthood in Colombia.Journal of epidemiology and community health · 2026Article
- Heavy drinking amplifies the risk of cardiometabolic multimorbidity attributed to adverse childhood experiences in middle-aged and older Chinese adults.MedScience · 2026Article
- Childhood Maltreatment and Cardiovascular Health: Role of Sex and Life's Essential 8 in the U.K. Biobank.JACC. Advances · 2026Article
- Racial/Ethnic variation in health insurance coverage and early midlife depressive symptoms in the U.S.BMC health services research · 2025Article
- Maternal adverse childhood experiences were associated with early screen exposure and prolonged daily screen time in preschool children.BMC public health · 2025Article
- Child Maltreatment Characteristics and Adult Physical Multimorbidity in Germany.JAMA network open · 2025Article
- The Mediating Effects of Chronic Diseases in the Relationship Between Adverse Childhood Experiences and Trajectories of Depressive Symptoms in Later Life: A Nationwide Longitudinal Study.Healthcare (Basel, Switzerland) · 2024Article
- Childhood maltreatment associated with adolescent peer networks: Withdrawal, avoidance, and fragmentation.Child abuse & neglect · 2024Article
- Early-life adversity predicting the incidence of multisite chronic pain in the general population.European psychiatry : the journal of the Association of European Psychiatrists · 2024Article
- The link between childhood physical activity enjoyment and adult kinesiophobia in individuals with chronic low back pain.BMC public health · 2024Article
- Contextualizing risk, pathways, and solutions for the relationship between adverse childhood experiences (ACEs) and type 2 diabetes among inner-city African Americans: A qualitative analysis and development of a theoretical framework.Journal of affective disorders · 2024Article
19 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 5 institutions in 1 country.
Funding
Abstract
objectiveAdverse events in childhood can indelibly influence adult health. While evidence for this association has mounted, a fundamental set of questions about how to operationalize adverse events has been understudied.
methodWe used data from the National Survey of Midlife Development in the United States to examine how quantity, timing, and types of adverse events in childhood are associated with adult cardiometabolic health.
resultsThe best-fitting specification of quantity of events was a linear measure reflecting a dose-response relationship. Timing of event mattered less than repeated exposure to events. Regarding the type of event, academic interruptions and sexual/physical abuse were most important. Adverse childhood events elevated the risk of diabetes and obesity similarly for men and women but had a greater impact on women's risk of heart disease. DISCUSSION: Findings demonstrate the insights that can be gleaned about the early-life origins of adult health by examining operationalization of childhood exposures.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.