Evidence map›Paper›PMID 25903721›Full record

ArticleJournal of clinical pharmacology2015

Antiretroviral therapy-induced toxicity is associated with increased mRNA expression of telomerase.

Min Li, Yram Foli, Nana Y Amakye, Taline Klein, Shanmugapriya Selvaraj, Lingeng Lu, Elijah Paintsil

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of clinical pharmacology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.2field-weighted citation impact, top 39% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 3 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 3 countries.

Min LiDepartment of Pediatrics, Yale School of Medicine, New Haven, CT, USA.
Yram FoliDepartment of Pediatrics, Yale School of Medicine, New Haven, CT, USA.
Nana Y AmakyeDepartment of Cell Physiology and Pharmacology, School of Biological Sciences, University of Leicester, Leicester, UK.
Taline KleinDepartment of Internal Medicine, University of São Paulo Medical School at Ribeirão Preto, São Paulo, Brazil.
Shanmugapriya SelvarajDepartment of Pediatrics, Yale School of Medicine, New Haven, CT, USA.
Lingeng LuDepartment of Epidemiology & Public Health, Yale School of Medicine, New Haven, CT, USA.
Elijah PaintsilDepartment of Pediatrics, Yale School of Medicine, New Haven, CT, USA.
Yale University · USUniversidade de São Paulo · BRUniversity of Leicester · GB

Funding

Using Coincidence Analysis to Investigate Factors Affecting PrEP Initiation and Continuation in Southern ending the Epidemic CountiesP30MH062294 · NIMH · YALE UNIVERSITY · PI John Edward Pachankis · 2001 to 2026
$48.5M
HIV Nucleoside Analogs Translational Studies: Resistance and MetabolismK08AI074404 · NIAID · YALE UNIVERSITY · PI PAINTSIL, ELIJAH · 2008 to 2012
$629k
NIAID NIH HHS K08 AI074404NIAID NIH HHS K08AI074404NIMH NIH HHS P30 MH062294
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

AgedCase-Control StudiesFemaleHIV InfectionsHumansMaleMiddle AgedReverse Transcriptase InhibitorsRNA, MessengerTelomeraseReverse Transcriptase InhibitorsRNA, MessengerTelomeraseTERT protein, humanantiretroviral therapyimmune activationmitochondrial toxicitytelomerasetelomere length

Identifiers

PMID25903721
PMCPMC4558235
OpenAlexW2121565261

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.