Evidence map›Paper›PMID 25903506›Full record

ArticleAIDS and behavior2015

Antiretroviral Therapy Use, Medication Adherence, and Viral Suppression Among PLWHA with Panic Symptoms.

Tanyka Suzanne Sam, Heidi E Hutton, Bryan Lau, Mary E McCaul, Jeanne Keruly, Richard Moore, Geetanjali Chander

Registry-linked trialAbstract read
In one paragraph

Article in AIDS and behavior, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04601064 (Peer Supported Collaborative Care to Increase Engagement in Mental Health and Substance Use Disorder Care in HIV Care Settings), which is not on this map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04601064 naactive not recruitingnot on this mapstarted 2022, after this paper: background citation

Peer Supported Collaborative Care to Increase Engagement in Mental Health and Substance Use Disorder Care in HIV Care Settings

TypeinterventionalSponsorJohns Hopkins UniversityRan2022 to 2026Enrolled405ConditionsHIV Infections, Substance Use Disorders, Mental Health Disorder, AddictionArmsCollaborative Care Model
3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Trial
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Tanyka Suzanne SamDepartment of Medicine, The Brooklyn Hospital Center, 121 Dekalb Avenue, Maynard Building, Suite 14D, Brooklyn, NY, 11201, USA. tss9008@nyp.org.
Heidi E HuttonDepartment of Psychiatry and Behavioral Sciences, Johns Hopkins University School of Medicine, Baltimore, MD, USA.
Bryan LauDepartment of Epidemiology, Johns Hopkins University Bloomberg School of Public Health, Baltimore, MD, USA.
Mary E McCaulDepartment of Psychiatry and Behavioral Sciences, Johns Hopkins University School of Medicine, Baltimore, MD, USA.
Jeanne KerulyDepartment of Medicine, Johns Hopkins University School of Medicine, Baltimore, MD, USA.
Richard MooreDepartment of Epidemiology, Johns Hopkins University Bloomberg School of Public Health, Baltimore, MD, USA.
Geetanjali ChanderDepartment of Medicine, Johns Hopkins University School of Medicine, Baltimore, MD, USA.

Funding

Vaccine Response and Immunotherapeutics SWGP30AI094189 · NIAID · JOHNS HOPKINS UNIVERSITY · PI Bryan Lau · 2012 to 2026
$67.0M
Johns Hopkins HIV Clinical CohortU01DA036935 · NIDA · JOHNS HOPKINS UNIVERSITY · PI MOORE, RICHARD DOUGLAS · 2014 to 2024
$14.9M
BEHAVIORAL RESEARCH IN HEART &VASCULAR DISEASET32HL007180 · NHLBI · JOHNS HOPKINS UNIVERSITY · PI MARUTHUR, NISA M · 1985 to 2020
$11.4M
HIV DISEASE OUTCOMES IN DRUG USERS IN CLINICAL PRACTICER01DA011602 · NIDA · JOHNS HOPKINS UNIVERSITY · PI MOORE, RICHARD DOUGLAS · 1998 to 2013
$10.8M
1/4 Alcohol Research Consortium in HIV-Administrative Core (ARCH-AC)U24AA020801 · NIAAA · JOHNS HOPKINS UNIVERSITY · PI CHANDER, GEETANJALI, MCCAUL, MARY E · 2011 to 2021
$3.5M
Brief Alcohol Intervention in HIV+ WomenR01AA014500 · NIAAA · JOHNS HOPKINS UNIVERSITY · PI MCCAUL, MARY E · 2003 to 2007
$1.7M
Alcohol and HIV Treatment and Clinical ProgressionR01AA016893 · NIAAA · JOHNS HOPKINS UNIVERSITY · PI MOORE, RICHARD DOUGLAS · 2008 to 2011
$1.3M
Alcohol and Psychiatric Comorbidity in HIV+ WomenK23AA015313 · NIAAA · JOHNS HOPKINS UNIVERSITY · PI CHANDER, GEETANJALI · 2005 to 2009
$875k
NHLBI NIH HHS 5T32-HL-007180NHLBI NIH HHS T32 HL007180NIAAA NIH HHS K23 AA015313NIAAA NIH HHS R01 AA014500NIAAA NIH HHS R01 AA016893NIAAA NIH HHS R01 AA14500NIAAA NIH HHS R01 AA16893NIAAA NIH HHS U01AA0120793NIAAA NIH HHS U24 AA020801NIAAA NIH HHS U24AA020801NIAID NIH HHS P30 AI094189NIDA NIH HHS R01 DA011602NIDA NIH HHS R01 DA11602NIDA NIH HHS U01 DA036935
6 · The paper itself

Abstract

Panic symptoms are prevalent among PLWHAs, yet few studies have examined their relationship with HIV outcomes. Using data from an observational cohort study in Baltimore, MD, we examined the association between panic symptoms and antiretroviral therapy (ART) use, medication adherence, and viral suppression. Data were analyzed using generalized estimating equations and adjusted for age, sex, race/ethnicity, cocaine and/or heroin use, clinic enrollment time, alcohol use, and depressive symptoms. Between June 2010 and September 2012, 1195 individuals participated in 2080 audio computer assisted interviews; 9.9 % (n = 118) of individuals endorsed current panic symptoms. In multivariate analysis, panic symptoms were associated with decreased ART use (IRR 0.94; p = 0.05). Panic symptoms were neither associated with medication adherence nor viral suppression. These findings were independent of depressive symptoms and substance use. Panic symptoms are under-recognized in primary care settings and present an important barrier to ART use. Further studies investigating the reasons for this association are needed.

Indexed as

Antiretroviral Therapy, Highly ActiveMedication AdherencePanicAdultAgedAlcohol DrinkingAnti-HIV AgentsBaltimoreCD4 Lymphocyte CountDepressionFemaleHIV InfectionsHumansMaleMiddle AgedProspective StudiesAnti-HIV AgentsAntiretroviral therapy useMedication adherencePanic symptomsPsychiatric disorderViral suppression

Identifiers

PMID25903506
PMCPMC4712641

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.