Evidence map›Paper›PMID 25903474›Full record

ArticleBMC surgery2015

Is gallbladder inflammation more severe in male patients presenting with acute cholecystitis?

Peter C Ambe, Sebastian A Weber, Dirk Wassenberg

Open access · goldAbstract read
In one paragraph

Article in BMC surgery, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
2.9field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 32 citations in OpenAlex.

  1. Article
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  4. Observational
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  7. Article
  8. A POPULATION STUDY ON GENDER AND ETHNICITY DIFFERENCES IN GALLBLADDER DISEASE IN BRAZIL.Arquivos brasileiros de cirurgia digestiva : ABCD = Brazilian archives of digestive surgery · 2022
    Article
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  11. Observational
  12. Surgical site infection following abdominal surgery: a prospective cohort studyCanadian journal of surgery. Journal canadien de chirurgie · 2019
    Article
  13. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Peter C AmbeDepartment of General, Visceral and thoracic surgery, St. Remigius Hospital Opladen, An St. Remigius 26, 51379, Leverkusen, Germany. peter.ambe@helios-kliniken.de.
Sebastian A WeberDepartment of Internal Medicine, St. Elisabeth Hospital Hohenlind, Werthmannstr. 1, 50937, Köln, Germany.
Dirk WassenbergDepartment of General, Visceral and thoracic surgery, St. Remigius Hospital Opladen, An St. Remigius 26, 51379, Leverkusen, Germany.
St. Remigius Krankenhaus Opladen · DESt. Elisabeth-Hospital Bochum · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe male gender is considered a risk factor for complications in patients undergoing laparoscopic cholecystectomy. The reasons for this gender associated risk are not clearly understood. The extent of gallbladder inflammation has been shown to influence surgical outcome. The aim of this study was to investigate whether or not gallbladder inflammation is more severe in male patients presenting with acute cholecystitis.

methodsA retrospective gender dependent comparison of the data of patients undergoing laparoscopic cholecystectomy for acute cholecystitis in a primary care facility within a five-year period was performed.

results138 patients, 69 males and 69 females were included for analysis. Severe gallbladder inflammation (gangrenous and necrotizing cholecystitis) was seen in a significant portion of the male population compared to the female population (p = 0.002). The male gender was confirmed in a multivariate analysis as an independent risk factor for severe cholecystits (p = 0.018).

conclusionThe male gender is a risk factor for severe gallbladder inflammation. An early surgical intervention may be needed to prevent complications.

Indexed as

AdultAgedCholecystectomy, LaparoscopicCholecystitis, AcuteFemaleGangreneHumansMaleMiddle AgedMultivariate AnalysisNecrosisRetrospective StudiesRisk FactorsSex Factors

Identifiers

PMID25903474
PMCPMC4415220
OpenAlexW2025822015

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.