Evidence map›Paper›PMID 25903356›Full record

ArticleClinical and vaccine immunology : CVI2015

Human Invasive Muscular Sarcocystosis Induces Th2 Cytokine Polarization and Biphasic Cytokine Changes, Based on an Investigation among Travelers Returning from Tioman Island, Malaysia.

Dennis Tappe, Günther Slesak, José Vicente Pérez-Girón, Johannes Schäfer, Andreas Langeheinecke, Gudrun Just-Nübling, César Muñoz-Fontela, Kerstin Püllmann

Open access · diamondAbstract read
In one paragraph

Article in Clinical and vaccine immunology : CVI, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.5field-weighted citation impact, top 37% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 5 citations in OpenAlex.

  1. Journal of parasitic diseases : official organ of the Indian Society for Parasitology · 2020
    Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 1 country.

Dennis TappeBernhard Nocht Institute for Tropical Medicine, Hamburg, Germany tappe@bnitm.de.
Günther SlesakTropenklinik Paul-Lechler-Hospital, Department of Tropical Medicine, Tübingen, Germany.
José Vicente Pérez-GirónHeinrich Pette Institute, Leibniz Institute for Experimental Virology, Hamburg, Germany.
Johannes SchäferTropenklinik Paul-Lechler-Hospital, Department of Tropical Medicine, Tübingen, Germany.
Andreas LangeheineckeMedizinische Klinik 1, Klinikum Saarbrücken, Saarbrücken, Germany.
Gudrun Just-NüblingKlinik II, Centre for Infectious and Tropical Diseases, J.W. Goethe University, Frankfurt/Main, Germany.
César Muñoz-FontelaBernhard Nocht Institute for Tropical Medicine, Hamburg, Germany Heinrich Pette Institute, Leibniz Institute for Experimental Virology, Hamburg, Germany German Centre for Infection Research (DZIF), partner site Hamburg-Luebeck-Borstel, Hamburg, Germany.
Kerstin PüllmannAescuLabor Hamburg, Hamburg, Germany.
Leibniz Institute of Virology (LIV) · DEBernhard Nocht Institute for Tropical Medicine · DEGoethe University Frankfurt · DEKlinikum Saarbrücken · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Sarcocystis nesbitti is a parasite responsible for a biphasic eosinophilic febrile myositis syndrome in two recent outbreaks in Malaysia. We demonstrate Th2 cytokine polarization in infected travelers, an overall cytokine production decrease in the early phase of the disease suggestive of initial immunosuppression, and elevated levels of proinflammatory and chemotactic cytokines in the later myositic phase.

Indexed as

AdolescentAdultChildCytokinesFemaleHumansImmune ToleranceMalaysiaMaleSarcocystisSarcocystosisTh2 CellsTravelYoung AdultCytokines

Identifiers

PMID25903356
PMCPMC4446401
OpenAlexW2192572204

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.