ReviewPediatric rheumatology online journal2015
Avascular necrosis in pediatric systemic lupus erythematosus: a brief report and review of the literature.
Review in Pediatric rheumatology online journal, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT00065806 (A Multicenter, Randomized, Double-Blind, Placebo-Controlled Study to Test the Safety and Efficacy of Lipitor), which is not on this map. Cited by 14 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
A Multicenter, Randomized, Double-Blind, Placebo-Controlled Study to Test the Safety and Efficacy of Lipitor (Atorvastatin) in Reducing the Progression of Carotid IMT in Early Childhood SLE
Who cites it
14 citing papers in PubMed, 36 citations in OpenAlex.
- Risk Factors for Corticosteroid-associated Osteonecrosis in Children: A National Database Study.Journal of the Pediatric Orthopaedic Society of North America · 2025Article
- Avascular necrosis in pediatric rheumatic diseases: an Italian retrospective multicentre study.Italian journal of pediatrics · 2025Article
- Evaluation of core decompression outcome in systemic lupus erythematosus with hip osteonecrosis: a retrospective cohort study.Advances in rheumatology (London, England) · 2024Article
- Update on Current Imaging of Systemic Lupus Erythematous in Adults and Juveniles.Journal of clinical medicine · 2022Review
- Epidemiology and risk factors associated with avascular necrosis in patients with autoimmune diseases: a nationwide study.The Korean journal of internal medicine · 2022Article
- Selective Ulnar Nerve Decompression, Capsular Branch Denervation, and Arthroscopic Debridement as a Unique Technique to Improve Quality of Life for Avascular Necrosis of the Distal Humerus and Radius in a Young Patient With ALL.Hand (New York, N.Y.) · 2022Article
- Glucocorticoid-induced osteonecrosis in systemic lupus erythematosus patients.Clinical and translational medicine · 2021Review
- Childhood-onset systemic lupus erythematosus with trisomy X and the increased risk for bone complications: a case report.Pediatric rheumatology online journal · 2021Article
- Risk factors for symptomatic Avascular Necrosis (AVN) in a multi-ethnic Systemic Lupus Erythematosus (SLE) cohort.PloS one · 2021Article
- Epidemiology and risk factors for avascular necrosis in childhood systemic lupus erythematosus in a Taiwanese population.Scientific reports · 2020Article
- Comorbidities of antiphospholipid syndrome and systemic lupus erythematosus in children.Current rheumatology reports · 2020Review
- Symptomatic multifocal avascular necrosis in an adolescent with neuropsychiatric systemic lupus erythematosus.Reumatologia · 2019Article
- OUTCOME OF FOUR PATIENTS WITH OSTEONECROSIS AFTER ONE-YEAR PAMIDRONATE TREATMENT.Acta endocrinologica (Bucharest, Romania : 2005)Article
- Utility of SPECT/CT in Non-Traumatic Osteonecrosis: Revisited with New Insights from a Prospective Diagnostic Study.Indian journal of nuclear medicine : IJNM : the official journal of the Society of Nuclear Medicine, IndiaArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors at 4 institutions in 1 country.
Funding
Abstract
unlabelledAvascular necrosis (AVN) occurs in several chronic illnesses, including systemic lupus erythematosus (SLE), but can also occur in healthy children. There are multiple theories to explain why and how AVN occurs, but an exact mechanism has yet to be unraveled. AVN in the pediatric lupus population is understudied. The Atherosclerosis Prevention in Pediatric Lupus Erythematosus (APPLE) trial, provides an excellent venue to conduct an exploratory analysis to assess associations between AVN and demographics, SLE disease activity and vitamin D deficiency. Herein we present a brief report describing our findings, as well as reviewing the literature on AVN in SLE and other entities.
trial registrationClinicalTrials.gov identifier: NCT00065806.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.