ArticleProceedings of the National Academy of Sciences of the United States of America2015
The genome of cultivated sweet potato contains Agrobacterium T-DNAs with expressed genes: An example of a naturally transgenic food crop.
Article in Proceedings of the National Academy of Sciences of the United States of America, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 83 papers, 1 of them a synthesis that pooled it.
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Who cites it
83 citing papers in PubMed, 1 synthesis or guideline pooled it, 275 citations in OpenAlex.
- Exploring and exploiting genetics and genomics for sweetpotato improvement: Status and perspectives.Plant communications · 2022Pooled it
- Article
- The afterlife of a horizontally transferred gene: Expansion and functional diversification of a C1A peptidase in wild Hordeum species.The plant genome · 2026Article
- The Promise of Synthetic Biology for Redesigning Plant Architecture.International journal of molecular sciences · 2026Review
- Specific features of rol-gene polymorphism of Rhizobium rhizogenes.Archives of microbiology · 2026Review
- Identification, Transcriptome, and Proteome Analysis of Expansin-like Subfamilies in the Storage Root AcrossPlants (Basel, Switzerland) · 2026Article
- Functional Analysis of Naturally IntegratedPlants (Basel, Switzerland) · 2025Article
- Effects of CP4-EPSPS-Containing Brassica juncea Hybrids on the Gut and Fecal Microbiota of the Terrestrial Decomposer Armadillidium vulgare.Microbial ecology · 2025Article
- Horizontal Gene Transfer in Plants and Implications for Biotechnology.Plant-environment interactions (Hoboken, N.J.) · 2025Review
- Mechanisms, detection, and impact of horizontal gene transfer in plant functional evolution.The Plant cell · 2025Review
- Phased chromosome-level assembly provides insight into the genome architecture of hexaploid sweetpotato.Nature plants · 2025Article
- Combining biotechnology with sustainability: feasibility of bioenergy sorghum in generating high-value bioproducts.Biotechnology letters · 2025Review
- Rethinking progress: harmonizing the discourse on genetically modified crops.Frontiers in plant science · 2025Review
- Stable transformation mediated byFrontiers in plant science · 2025Article
- Naturally transgenic plants and the need to rethink regulatory triggers in biotechnology.Frontiers in bioengineering and biotechnology · 2025Article
- Review
- Chromosomal Localization and Diversity Analysis of 5S and 18S Ribosomal DNA in 13 Species from the GenusGenes · 2024Article
- Transcriptional landscape of sweetpotato root tip development at the single-cell level.BMC plant biology · 2024Article
- Superior osmotic stress tolerance in oilseed rape transformed with wild-type Rhizobium rhizogenes.Plant cell reports · 2024Article
- Evolutionary Fate of the Opine Synthesis Genes in theBiology · 2024Article
23 more citing papers are in PubMed but not listed here.
Corrections and comments
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Authors and funding
8 authors at 4 institutions in 4 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Agrobacterium rhizogenes and Agrobacterium tumefaciens are plant pathogenic bacteria capable of transferring DNA fragments [transfer DNA (T-DNA)] bearing functional genes into the host plant genome. This naturally occurring mechanism has been adapted by plant biotechnologists to develop genetically modified crops that today are grown on more than 10% of the world's arable land, although their use can result in considerable controversy. While assembling small interfering RNAs, or siRNAs, of sweet potato plants for metagenomic analysis, sequences homologous to T-DNA sequences from Agrobacterium spp. were discovered. Simple and quantitative PCR, Southern blotting, genome walking, and bacterial artificial chromosome library screening and sequencing unambiguously demonstrated that two different T-DNA regions (IbT-DNA1 and IbT-DNA2) are present in the cultivated sweet potato (Ipomoea batatas [L.] Lam.) genome and that these foreign genes are expressed at detectable levels in different tissues of the sweet potato plant. IbT-DNA1 was found to contain four open reading frames (ORFs) homologous to the tryptophan-2-monooxygenase (iaaM), indole-3-acetamide hydrolase (iaaH), C-protein (C-prot), and agrocinopine synthase (Acs) genes of Agrobacterium spp. IbT-DNA1 was detected in all 291 cultigens examined, but not in close wild relatives. IbT-DNA2 contained at least five ORFs with significant homology to the ORF14, ORF17n, rooting locus (Rol)B/RolC, ORF13, and ORF18/ORF17n genes of A. rhizogenes. IbT-DNA2 was detected in 45 of 217 genotypes that included both cultivated and wild species. Our finding, that sweet potato is naturally transgenic while being a widely and traditionally consumed food crop, could affect the current consumer distrust of the safety of transgenic food crops.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.