Evidence map›Paper›PMID 25902473›Full record

ArticleImmunity2015

Thinking outside the gate: single-cell assessments in multiple dimensions.

Pia Kvistborg, Cécile Gouttefangeas, Nima Aghaeepour, Angelica Cazaly, Pratip K Chattopadhyay, Cliburn Chan, Judith Eckl, Greg Finak, Sine Reker Hadrup, Holden T Maecker and 8 more

Abstract readLetter
In one paragraph

Article in Immunity, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers.

0numbers the graph read from it
0cells of the map it votes in
29citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

29 citing papers in PubMed.

  1. Trial
  2. Review
  3. Article
  4. Article
  5. A Cancer Biologist's Primer on Machine Learning Applications in High-Dimensional Cytometry.Cytometry. Part A : the journal of the International Society for Analytical Cytology · 2020
    Review
  6. Article
  7. Review
  8. Computational Analysis of Multiparametric Flow Cytometric Data to Dissect B Cell Subsets in Vaccine Studies.Cytometry. Part A : the journal of the International Society for Analytical Cytology · 2020
    Article
  9. Improving the Rigor and Reproducibility of Flow Cytometry-Based Clinical Research and Trials Through Automated Data Analysis.Cytometry. Part A : the journal of the International Society for Analytical Cytology · 2020
    Article
  10. Article
  11. Article
  12. Data-Driven Flow Cytometry Analysis.Methods in molecular biology (Clifton, N.J.) · 2019
    Review
  13. Article
  14. Supervised Machine Learning with CITRUS for Single Cell Biomarker Discovery.Methods in molecular biology (Clifton, N.J.) · 2019
    Article
  15. Article
  16. CytoML for cross-platform cytometry data sharing.Cytometry. Part A : the journal of the International Society for Analytical Cytology · 2018
    Article
  17. Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

18 authors.

Pia KvistborgNetherlands Cancer Institute, 1006 BE Amsterdam, the Netherlands.
Cécile GouttefangeasInstitute for Cell Biology, Department of Immunology, University of Tübingen, 72076 Tuebingen, Germany.
Nima AghaeepourTerry Fox Laboratory, BC Cancer Agency, Vancouver, BC V5Z 1L3, Canada.
Angelica CazalyUniversity of Southampton, Southampton SO17 1BJ, UK.
Pratip K ChattopadhyayImmunoTechnology Section, Vaccine Research Center, NIH, Bethesda, MD 20892, USA.
Cliburn ChanDepartment of Biostatistics and Bioinformatics, Duke University Medical Center, Durham, NC 27710, USA.
Judith EcklHelmholtz Zentrum München, 85764 Neuherberg, Germany.
Greg FinakVaccine and Infectious Disease Division, Department of Biostatistics, Bioinformatics, and Epidemiology, Fred Hutchinson Cancer Research Center, Seattle, WA 98155, USA.
Sine Reker HadrupCenter for Cancer Immune Therapy, Herlev Hospital, 2730 Herlev, Denmark.
Holden T MaeckerInstitute for Immunity, Transplantation, and Infection, Stanford School of Medicine, Stanford University, Stanford, CA 94305, USA.
Dominik MaurerImmatics Biotechnologies GmbH, 72076 Tübingen, Germany.
Tim MosmannDavid D. Smith Center for Vaccine Biology and Immunology, University of Rochester Medical Center, Rochester, NY 14642, USA.
Peng QiuWallace H. Coulter Department of Biomedical Engineering, Georgia Institute of Technology and Emory University School of Medicine, Atlanta, GA 30322, USA.
Richard H ScheuermannJ. Craig Venter Institute, La Jolla, CA 92037, USA; Department of Pathology, University of California, San Diego, San Diego, CA 92093, USA.
Marij J P WeltersDepartment of Clinical Oncology, Leiden University Medical Center, 2300 RA Leiden, the Netherlands.
Guido FerrariDepartment of Surgery, Duke University Medical Center, Durham, NC 27710, USA.
Ryan R BrinkmanTerry Fox Laboratory, BC Cancer Agency, Vancouver, BC V5Z 1L3, Canada. Electronic address: rbrinkman@bccrc.ca.
Cedrik M BrittenBioNTech RNA Pharmaceuticals GmbH, 55131 Mainz, Germany. Electronic address: cebritten@web.de.

Funding

Human Immunology Center at the University of RochesterR24AI054953 · NIAID · UNIVERSITY OF ROCHESTER · PI MOSMANN, TIM R. · 2003 to 2012
$8.8M
The Statistical and Computational Analysis of Flow Cytometry DataR01EB008400 · NIBIB · FRED HUTCHINSON CANCER RESEARCH CENTER · PI GOTTARDO, RAPHAEL · 2008 to 2015
$2.9M
Identifying the cellular hierarchy and drug response of AML using cytometric dataR01CA163481 · NCI · UNIVERSITY OF TX MD ANDERSON CAN CTR · PI QIU, PENG · 2012 to 2015
$1.1M
NCI NIH HHS R01 CA163481NIAID NIH HHS R24 AI054953NIBIB NIH HHS R01 EB008400
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

SoftwareBiomarkersComputational BiologyFlow CytometryHumansImmunityLymphocytesSingle-Cell AnalysisBiomarkers

Identifiers

PMID25902473
PMCPMC4824634

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.