Evidence map›Paper›PMID 25901907›Full record

ArticleJournal of biomechanical engineering2015

Development and Validation of a Musculoskeletal Model of the Fully Articulated Thoracolumbar Spine and Rib Cage.

Alexander G Bruno, Mary L Bouxsein, Dennis E Anderson

Abstract readValidation Study
In one paragraph

Article in Journal of biomechanical engineering, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 72 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
72citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

72 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Article
  4. Abdominal wall tension after spinal deformity correction compromises postoperative biomechanics and may contribute to proximal junctional kyphosis.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2026
    Article
  5. A stiffness-dependent method to estimate spine kinematics and loading reveals the impact of nonlinear mechanics during lifting tasks.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2026
    Article
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  8. Machine learning outperforms anthropometric scaling in predicting muscle parameters and spinal loading: a subject-specific musculoskeletal modeling study.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2026
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  16. Review
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  18. The triadic relationship between spinal posture, loading, and degeneration.Frontiers in bioengineering and biotechnology · 2025
    Article
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  20. Article

12 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Alexander G Bruno
Mary L Bouxsein
Dennis E Anderson

Funding

Biomechanics of Vertebral Fracture: The Framingham QCT StudyR01AR053986 · NIAMS · BETH ISRAEL DEACONESS MEDICAL CENTER · PI BOUXSEIN, MARY L · 2007 to 2016
$5.4M
Age-related Changes in Thoracic Spine BiomechanicsK99AG042458 · NIA · BETH ISRAEL DEACONESS MEDICAL CENTER · PI ANDERSON, DENNIS · 2013 to 2014
$179k
Biomechanics of the Vertebral Fracture CascadeF31AG041629 · NIA · BETH ISRAEL DEACONESS MEDICAL CENTER · PI BRUNO, ALEXANDER GREGORY · 2011 to 2015
$154k
THE FRAMINGHAM HEART STUDY-N01HC25195-268025195-268025195N01HC025195 · HC · TRUSTEES OF BOSTON UNIVERSITY · PI WOLF, PHILIP A · 2002 to 2006
–
NHLBI NIH HHS N01 HC025195NHLBI NIH HHS N01-HC-25195NIAMS NIH HHS R01 AR053986NIAMS NIH HHS R01AR053986NIA NIH HHS F31 AG041629NIA NIH HHS F31AG041629NIA NIH HHS K99 AG042458NIA NIH HHS K99AG042458
6 · The paper itself

Abstract

We developed and validated a fully articulated model of the thoracolumbar spine in opensim that includes the individual vertebrae, ribs, and sternum. To ensure trunk muscles in the model accurately represent muscles in vivo, we used a novel approach to adjust muscle cross-sectional area (CSA) and position using computed tomography (CT) scans of the trunk sampled from a community-based cohort. Model predictions of vertebral compressive loading and trunk muscle tension were highly correlated to previous in vivo measures of intradiscal pressure (IDP), vertebral loading from telemeterized implants and trunk muscle myoelectric activity recorded by electromyography (EMG).

Indexed as

Models, AnatomicAdultElectromyographyHumansLumbar VertebraeMaleMusclesMuscle TonusProstheses and ImplantsRibsThoracic VertebraeTomography, X-Ray ComputedWeight-Bearing

Identifiers

PMID25901907
PMCPMC5101035

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.