Trial reportThoracic surgery clinics2015
Results of the national lung cancer screening trial: where are we now?
Trial report in Thoracic surgery clinics, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 16 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
16 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Pooled it
- Breath-based lung cancer detection using an ML-driven low-cost sensor array.Scientific reports · 2025Article
- Lung Cancer-Epidemiology, Pathogenesis, Treatment and Molecular Aspect (Review of Literature).International journal of molecular sciences · 2025Review
- Next generation performance status: digital health technologies across the lung cancer continuum.Frontiers in digital health · 2025Review
- Examining implementation strategies to reduce disparities in lung cancer screening uptake by state Medicaid expansion status: a scoping review.Preventive oncology & epidemiology · 2025Article
- Article
- The Effect of COVID-19 on Lung Cancer Screening.Cureus · 2024Article
- Economic Evaluation of a Novel Lung Cancer Diagnostic in a Population of Patients with a Positive Low-Dose Computed Tomography Result.Journal of health economics and outcomes research · 2024Article
- The cognitive and perceptual processes that affect observer performance in lung cancer detection: a scoping review.Journal of medical radiation sciences · 2021Article
- Downregulated microRNA-140-5p expression regulates apoptosis, migration and invasion of lung cancer cells by targeting zinc finger protein 800.Oncology letters · 2020Article
- Article
- Non-invasive Detection of Exosomal MicroRNAs via Tethered Cationic Lipoplex Nanoparticles (tCLN) Biochip for Lung Cancer Early Detection.Frontiers in genetics · 2020Article
- Lobar or sublobar resections are safe procedures for management of early lung cancer.Annals of translational medicine · 2019Article
- An Immuno-Biochip Selectively Captures Tumor-Derived Exosomes and Detects Exosomal RNAs for Cancer Diagnosis.ACS applied materials & interfaces · 2018Article
- Recent Advances in Exosomal Protein Detection Via Liquid Biopsy Biosensors for Cancer Screening, Diagnosis, and Prognosis.The AAPS journal · 2018Review
- Article
Corrections and comments
- Erratum issuedErratum.2020
Authors and funding
7 authors.
Funding
Abstract
The National Lung Screening Trial was a large, multicenter, randomized controlled trial published in 2011. It found that annual screening with low-dose CT (LDCT) in a high-risk population was associated with a 20% reduction in lung cancer-specific mortality compared with conventional chest radiography. Several leading professional organizations have since put forth lung cancer screening guidelines that include the use of LDCT, largely on the basis of this study. Broad adoption of these screening recommendations, however, remains a challenge.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.