ArticleJournal of the American Geriatrics Society2015
Transmission and effect of multiple clusters of seasonal influenza in a Swiss geriatric hospital.
Article in Journal of the American Geriatrics Society, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
23 citing papers in PubMed, 46 citations in OpenAlex.
- Comparison of 28-Day Mortality Between Hospital- and Community-Acquired Influenza Patients.Infectious diseases & clinical microbiology · 2023Article
- A Cold Case of Equine Influenza Disentangled with Nanopore Sequencing.Animals : an open access journal from MDPI · 2023Article
- An anti-influenza combined therapy assessed by single cell RNA-sequencing.Communications biology · 2022Article
- Strategies to prevent ventilator-associated pneumonia, ventilator-associated events, and nonventilator hospital-acquired pneumonia in acute-care hospitals: 2022 Update.Infection control and hospital epidemiology · 2022Article
- Seasonal influenza vaccination of healthcare workers: a narrative review.International journal of occupational medicine and environmental health · 2022Review
- Secondary attack rates from asymptomatic and symptomatic influenza virus shedders in hospitals: Results from the TransFLUas influenza transmission study.Infection control and hospital epidemiology · 2022Article
- Transmission visualizations of healthcare infection clusters: A scoping review.Antimicrobial stewardship & healthcare epidemiology : ASHE · 2022Article
- We are not doing enough to prevent the spread of COVID-19 and other respiratory viruses in Australian hospitals.The Medical journal of Australia · 2021Review
- Pneumonia prevention in the elderly patients: the other sides.Aging clinical and experimental research · 2021Article
- Influenza Vaccination Hesitancy among Healthcare Workers in South Al Batinah Governorate in Oman: A Cross-Sectional Study.Vaccines · 2020Article
- Are healthcare workers more likely than the general population to consult in primary care for an influenza-like illness? Results from a case-control study.Influenza and other respiratory viruses · 2020Article
- Nosocomial transmission of influenza: A retrospective cross-sectional study using next generation sequencing at a hospital in England (2012-2014).Influenza and other respiratory viruses · 2019Article
- Article
- A rapid evidence appraisal of influenza vaccination in health workers: An important policy in an area of imperfect evidence.Vaccine: X · 2019Review
- Clinical Practice Guidelines by the Infectious Diseases Society of America: 2018 Update on Diagnosis, Treatment, Chemoprophylaxis, and Institutional Outbreak Management of Seasonal Influenzaa.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2019Article
- Molecular characterization of a nosocomial outbreak of influenza B virus in an acute care hospital setting.The Journal of hospital infection · 2019Article
- Factors associated with influenza vaccination among healthcare workers in acute care hospitals in Canada.Influenza and other respiratory viruses · 2018Article
- Use of Genome Sequencing to Define Institutional Influenza Outbreaks, Toronto, Ontario, Canada, 2014-15.Emerging infectious diseases · 2018Article
- Assessing the reporting quality of influenza outbreaks in the community.Influenza and other respiratory viruses · 2017Article
- Influenza in long-term care facilities.Influenza and other respiratory viruses · 2017Review
Corrections and comments
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Authors and funding
9 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectivesTo investigate a nosocomial outbreak of influenza.
designProspective outbreak investigation with active case finding and molecular typing.
settingA large academic geriatric hospital in Switzerland.
participantsElderly hospitalized adults. MEASUREMENTS: Based on syndromic surveillance, a nosocomial influenza outbreak was suspected in February 2012. All suspected cases were screened for respiratory viruses using real-time reverse transcription polymerase chain reaction of nasopharyngeal swabs. Infection control procedures (droplet precautions with single room isolation whenever possible) were implemented for all suspected or confirmed cases. Specimens positive for influenza viruses were processed and sequenced whenever possible to track transmission dynamics.
resultsRespiratory samples from 155 suspected cases were analyzed during the outbreak period, of which 69 (44%) were positive for influenza virus, 26 (17%) were positive for other respiratory viruses, and 60 (39%) were negative. Three other cases fulfilled clinical criteria for influenza infection but were not sampled, and one individual was admitted with an already positive test, resulting in a total of 73 influenza cases, of which 62 (85%) were classified as nosocomial. Five distinct clusters of nosocomial transmission were identified using viral sequencing, with epidemiologically unexpected in-hospital transmission dynamics. Seven of 23 patients who experienced influenza complications died. Sixteen healthcare workers experienced an influenza-like illness (overall vaccination rate, 36%).
conclusionNosocomial influenza transmission caused more secondary cases than repeated community importation during this polyclonal outbreak. Molecular tools revealed complex transmission dynamics. Low healthcare worker vaccination rates and gaps in recommended infection control procedures are likely to have contributed to nosocomial spread of influenza, which remains a potentially life-threatening disease in elderly adults.
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