Evidence map›Paper›PMID 25900234›Full record

Trial reportJournal of oral and maxillofacial surgery : official journal of the American Association of Oral and Maxillofacial Surgeons2015

Postdischarge Nausea and Vomiting Remains Frequent After Le Fort I Osteotomy Despite Implementation of a Multimodal Antiemetic Protocol Effective in Reducing Postoperative Nausea and Vomiting.

Carolyn Dicus Brookes, Timothy A Turvey, Ceib Phillips, Vincent Kopp, Jay A Anderson

Open access · greenAbstract readClinical TrialComparative Study
PubMed Full text at PMC Publisher
In one paragraph

Trial report in Journal of oral and maxillofacial surgery : official journal of the American Association of Oral and Maxillofacial Surgeons, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.6field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 10 citations in OpenAlex.

  1. Postdischarge Nausea and Vomiting and Co-occurring Symptoms in Women Following Breast Cancer Surgery.Journal of perianesthesia nursing : official journal of the American Society of PeriAnesthesia Nurses · 2023
    Observational
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Carolyn Dicus BrookesChief Resident, Department of Oral and Maxillofacial Surgery, University of North Carolina-Chapel Hill, Chapel Hill, NC.
Timothy A TurveyProfessor and Chairman, Department of Oral and Maxillofacial Surgery, University of North Carolina-Chapel Hill, Chapel Hill, NC.
Ceib PhillipsProfessor, Department of Orthodontics, University of North Carolina-Chapel Hill, Chapel Hill, NC.
Vincent KoppProfessor, Department of Anesthesiology, University of North Carolina-Chapel Hill, Chapel Hill, NC.
Jay A AndersonAssociate Professor, Departments of Anesthesiology and Oral and Maxillofacial Surgery, University of North Carolina-Chapel Hill, Chapel Hill, NC. Electronic address: janderson@aims.unc.edu.
University of North Carolina at Chapel Hill · US

Funding

INFLUENCES ON STABILITY FOLLOWING ORTHOGNATHIC SURGERYR01DE005215 · NIDCR · UNIV OF NORTH CAROLINA CHAPEL HILL · PI PHILLIPS, CEIB · 1985 to 2013
$6.3M
NIDCR NIH HHS R01 DE 005215NIDCR NIH HHS R01 DE005215
6 · The paper itself

Abstract

purposeTo assess the prevalence of postdischarge nausea and vomiting (PDNV) after Le Fort I osteotomy with and without the use of a multimodal antiemetic protocol shown to decrease postoperative nausea and vomiting (PONV). MATERIALS AND

methodsConsecutive patients undergoing Le Fort I osteotomy with or without additional procedures at a single academic institution formed the intervention cohort for an institutional review board-approved prospective clinical trial with a retrospective comparison group. The intervention cohort was managed with a multimodal antiemetic protocol. The comparison group consisted of consecutive patients who underwent similar surgical procedures at the same institution before protocol implementation. All patients were asked to complete a postdischarge diary documenting the occurrence of nausea and vomiting. Those who completed the diaries were included in this analysis. Data were analyzed with the Fisher exact test and the Wilcoxon rank sum test. A P value less than .05 was considered significant.

resultsDiaries were completed by 85% of patients in the intervention group (79 of 93) and 75% of patients in the comparison group (103 of 137). Patients in the intervention (n = 79) and comparison (n = 103) groups were similar in the proportion of patients with validated risk factors for PDNV, including female gender, history of PONV, age younger than 50 years, opioid use in the postanesthesia care unit (PACU), and nausea in the PACU (P = .37). The prevalence of PDNV was unaffected by the antiemetic protocol. After discharge, nausea was reported by 72% of patients in the intervention group and 60% of patients in the comparison group (P = .13) and vomiting was reported by 22% of patients in the intervention group and 29% of patients in the comparison group (P = .40).

conclusionModalities that successfully address PONV after Le Fort I osteotomy might fail to affect PDNV, which is prevalent in this population. Future investigation will focus on methods to minimize PDNV.

Indexed as

AdolescentAdultAge FactorsAnesthesia Recovery PeriodAntiemeticsCohort StudiesDiphenhydramineFemaleFollow-Up StudiesHumansMaleMedical RecordsMiddle AgedNarcoticsOndansetronOsteotomy, Le FortAntiemeticsDiphenhydramineesmololNarcoticsOndansetronPropanolamines

Identifiers

PMID25900234
PMCPMC4475450
OpenAlexW1988638061

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.