Evidence map›Paper›PMID 25899791›Full record

Trial reportPsychopharmacology2015

β-Adrenoceptor blockade modulates fusiform gyrus activity to black versus white faces.

S Terbeck, G Kahane, S McTavish, R McCutcheon, M Hewstone, J Savulescu, L P Chesterman, P J Cowen, R Norbury

Open access · hybridAbstract readRandomized Controlled Trial
In one paragraph

Trial report in Psychopharmacology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
7.5field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 14 citations in OpenAlex.

  1. Article
  2. A meta-analysis of procedures to change implicit measures.Journal of personality and social psychology · 2019
    Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 5 institutions in 1 country.

S TerbeckDepartment of Psychology, University of Plymouth, Drake Circus, Plymouth, PL48AA, UK, sylvia.terbeck@psy.ox.ac.uk.
G Kahane
S McTavish
R McCutcheon
M Hewstone
J Savulescu
L P Chesterman
P J Cowen
R Norbury
University of Oxford · GBWarneford Hospital · GBUniversity of Nottingham · GBUniversity of Plymouth · GBUniversity of Roehampton · GB

Funding

Wellcome Trust 086041Wellcome Trust WT086041MAWellcome Trust WT087208MF
6 · The paper itself

Abstract

introductionThe beta-adrenoceptor antagonist propranolol is known to reduce peripheral and central activity of noradrenaline. A recent study found that intervention with propranolol diminished negative implicit racial bias. MATERIALS AND

methodThe current study used functional magnetic resonance imaging (fMRI) in order to determine the neural correlates of this effect. Healthy volunteers (N = 40) of white ethnic origin received a single oral dose (40 mg) of propranolol, in a randomised, double-blind, parallel group, placebo-controlled design, before viewing unfamiliar faces of same and other race. RESULTS AND DISCUSSION: We found significantly reduced activity in the fusiform gyrus and thalamus following propranolol to out-group faces only. Additionally, propranolol lowered the implicit attitude score, without affecting explicit prejudice measure.

conclusionThese findings suggest that noradrenaline pathways might modulate racial bias by acting on the processing of categorisation in the fusiform gyrus.

Indexed as

FacePrejudiceAdrenergic beta-AntagonistsAttitudeBlack or African AmericanDouble-Blind MethodFemaleHumansMagnetic Resonance ImagingMalePhotic StimulationPropranololTemporal LobeWhite PeopleYoung AdultAdrenergic beta-AntagonistsPropranolol

Identifiers

PMID25899791
PMCPMC4513220
OpenAlexW2064560024

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.