Evidence map›Paper›PMID 25899747›Full record

ArticleTrends in parasitology2015

Apicomplexan cell cycle flexibility: centrosome controls the clutch.

Chun-Ti Chen, Marc-Jan Gubbels

Abstract readComment
In one paragraph

Article in Trends in parasitology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed.

  1. Article
  2. The Centrocone Protein SMC_N1 Is Important for the Proliferation ofAnimals : an open access journal from MDPI · 2026
    Article
  3. Article
  4. Article
  5. Article
  6. Review
  7. Article
  8. Review
  9. Review
  10. Article
  11. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

2 authors.

Chun-Ti ChenDepartment of Biology, Boston College, Chestnut Hill, MA 02467, USA.
Marc-Jan GubbelsDepartment of Biology, Boston College, Chestnut Hill, MA 02467, USA. Electronic address: gubbelsj@bc.edu.

Funding

Cytoskeleton scaffold assembly in Toxoplasma gondiiR01AI081924 · NIAID · BOSTON COLLEGE · PI GUBBELS, MARC-JAN · 2009 to 2012
$1.4M
Organization of Toxoplasma invasion and cell division by EF-hand proteinsR03AI107475 · NIAID · BOSTON COLLEGE · PI GUBBELS, MARC-JAN · 2013 to 2014
$157k
NIAID NIH HHS AI081924NIAID NIH HHS AI107475NIAID NIH HHS R01 AI081924NIAID NIH HHS R03 AI107475
6 · The paper itself

Abstract

The centrosome serves as a central hub coordinating multiple cellular events in eukaryotes. A recent study in Toxoplasma gondii revealed a unique bipartite structure of the centrosome, which coordinates the nuclear cycle (S-phase and mitosis) and budding cycle (cytokinesis) of the parasite, and deciphers the principle behind flexible apicomplexan cell division modes.

Indexed as

Cell Nucleus DivisionCytokinesisCell Cycle ProteinsCentrosomeHumansProtozoan ProteinsToxoplasmaCell Cycle ProteinsProtozoan ProteinsapicomplexacentrosomeendodyogenyschizogonyToxoplasma gondii

Identifiers

PMID25899747
PMCPMC4459897

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.