Evidence map›Paper›PMID 25898992›Full record

Observational studyScandinavian journal of trauma, resuscitation and emergency medicine2015

Quality of cardiopulmonary resuscitation in out-of-hospital cardiac arrest before and after introduction of a mechanical chest compression device, LUCAS-2; a prospective, observational study.

Tinne Tranberg, Jens F Lassen, Anne K Kaltoft, Troels M Hansen, Carsten Stengaard, Lars Knudsen, Sven Trautner, Christian J Terkelsen

Open access · goldAbstract readObservational Study
In one paragraph

Observational study in Scandinavian journal of trauma, resuscitation and emergency medicine, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed, 1 pooled it
6.5field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 1 synthesis or guideline pooled it, 65 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Tinne TranbergDepartment of Cardiology, Aarhus University Hospital, Aarhus, Denmark. tinne.tranberg@clin.au.dk.
Jens F LassenDepartment of Cardiology, Aarhus University Hospital, Aarhus, Denmark. jens.lassen@clin.au.dk.
Anne K KaltoftDepartment of Cardiology, Aarhus University Hospital, Aarhus, Denmark. anne.kaltoft@clin.au.dk.
Troels M HansenDepartment of Prehospital Medical Care Service, Central Denmark Region, Aarhus, Denmark. troehans@rm.dk.
Carsten StengaardDepartment of Cardiology, Aarhus University Hospital, Aarhus, Denmark. carsten.stengaard@clin.au.dk.
Lars KnudsenHelicopter Emergency Medical Service, Central Denmark Region, Aarhus, Denmark. lars.knudsen@dadlnet.dk.
Sven TrautnerFalck A/S, Copenhagen, Denmark. st@falck.dk.
Christian J TerkelsenDepartment of Cardiology, Aarhus University Hospital, Aarhus, Denmark. christian.juhl.terkelsen@clin.au.dk.
Aarhus University Hospital · DKCentral Denmark Region · DK

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundMechanical chest compressions have been proposed to provide high-quality cardiopulmonary resuscitation (CPR), but despite the growing use of mechanical chest compression devices, only few studies have addressed their impact on CPR quality. This study aims to evaluate mechanical chest compressions provided by LUCAS-2 (Lund University Cardiac Assist System) compared with manual chest compression in a cohort of out-of-hospital cardiac arrest (OHCA) cases.

methodsIn this prospective study conducted in the Central Denmark Region, Denmark, the emergency medical service attempted resuscitation and reported data on 696 non-traumatic OHCA patients between April 2011 and February 2013. Of these, 155 were treated with LUCAS CPR after an episode with manual CPR. The CPR quality was evaluated using transthoracic impedance measurements collected from the LIFEPAK 12 defibrillator, and the effect was assessed in terms of chest compression rate, no-flow time and no-flow fraction; the fraction of time during resuscitation in which the patient is without spontaneous circulation receiving no chest compression.

resultsThe median total episode duration was 21 minutes, and the episode with LUCAS CPR was significantly longer than the manual CPR episode, 13 minutes vs. 5 minutes, p < 0.001. The no-flow fraction was significantly lower during LUCAS CPR (16%) than during manual CPR (35%); difference 19% (95% CI: 16% to 21%; p < 0.001). No differences were found in pre- and post-shock no-flow time throughout manual CPR and LUCAS CPR. Contrary to the manual CPR, the average compression rate during LUCAS CPR was in conformity with the current Guidelines for Resuscitation, 102/minute vs. 124/minute, p < 0.001.

conclusionMechanical chest compressions provided by the LUCAS device improve CPR quality by significantly reducing the NFF and by improving the quality of chest compression compared with manual CPR during OHCA resuscitation. However, data on end-tidal Co2 and chest compression depth surrogate parameters of CPR quality could not be reported.

Indexed as

AgedDenmarkFemaleHeart MassageHumansMaleOut-of-Hospital Cardiac ArrestProspective StudiesSignal Processing, Computer-AssistedSoftwareTime FactorsTreatment Outcome

Identifiers

PMID25898992
PMCPMC4411930
OpenAlexW2140751054

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.