Evidence map›Paper›PMID 25898341›Full record

Trial reportBehaviour research and therapy2015

An open trial of Acceptance-based Separated Family Treatment (ASFT) for adolescents with anorexia nervosa.

C Alix Timko, Nancy L Zucker, James D Herbert, Daniel Rodriguez, Rhonda M Merwin

Open access · greenAbstract readClinical Trial
In one paragraph

Trial report in Behaviour research and therapy, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
5.3field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 58 citations in OpenAlex.

  1. Trial
  2. Article
  3. Does Evidence Support an Emotion Regulation Model of Anorexia Nervosa? A Systematic Review of Over a Decade of Research.Clinical psychology : a publication of the Division of Clinical Psychology of the American Psychological Association · 2025
    Article
  4. Review
  5. Family accommodation in PTSD: Proposed considerations and distinctions from the established transdiagnostic literature.Clinical psychology : a publication of the Division of Clinical Psychology of the American Psychological Association · 2023
    Article
  6. Randomized Clinical Trial EvaluatingJournal of clinical medicine · 2022
    Article
  7. Article
  8. Review
  9. Article
  10. Article
  11. Review
  12. Article
  13. Article
  14. Review
  15. Article
  16. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 5 institutions in 1 country.

C Alix TimkoDepartment of Behavioral and Social Sciences, University of the Sciences, 600 S. 43rd St, Philadelphia, PA 19063, USA; Department of Psychology, Towson University, 8000 York Rd., Towson, MD 21252, USA. Electronic address: TIMKOC@email.chop.edu.
Nancy L ZuckerDepartment of Psychology and Neuroscience, Duke University, Durham, NC 27710, USA; Department of Psychiatry and Behavioral Sciences, Duke University Medical Center, Durham, NC, USA.
James D HerbertDepartment of Psychology, Drexel University, Philadelphia, PA 19104, USA.
Daniel RodriguezDepartment of Urban Public Health and Nutrition, La Salle University, Philadelphia, PA 19141, USA.
Rhonda M MerwinDepartment of Psychiatry and Behavioral Sciences, Duke University Medical Center, Durham, NC, USA.
Drexel University · USDuke Medical Center · USDuke University · USLa Salle University · USUniversity of the Sciences · US

Funding

Acceptance-Based Separated Family Treatment for Adolescent Anorexia NervosaR21MH085975 · NIMH · TOWSON UNIVERSITY · PI TIMKO, C. ALIX · 2009 to 2010
$406k
NIMH NIH HHS R21 MH085975NIMH NIH HHS R21MH085975
6 · The paper itself

Abstract

Family based-treatments have the most empirical support in the treatment of adolescent anorexia nervosa; yet, a significant percentage of adolescents and their families do not respond to manualized family based treatment (FBT). The aim of this open trial was to conduct a preliminary evaluation of an innovative family-based approach to the treatment of anorexia: Acceptance-based Separated Family Treatment (ASFT). Treatment was grounded in Acceptance and Commitment Therapy (ACT), delivered in a separated format, and included an ACT-informed skills program. Adolescents (ages 12-18) with anorexia or sub-threshold anorexia and their families received 20 treatment sessions over 24 weeks. Outcome indices included eating disorder symptomatology reported by the parent and adolescent, percentage of expected body weight achieved, and changes in psychological acceptance/avoidance. Half of the adolescents (48.0%) met criteria for full remission at the end of treatment, 29.8% met criteria for partial remission, and 21.3% did not improve. Overall, adolescents had a significant reduction in eating disorder symptoms and reached expected body weight. Treatment resulted in changes in psychological acceptance in the expected direction for both parents and adolescents. This open trial provides preliminary evidence for the feasibility, acceptability, and efficacy of ASFT for adolescents with anorexia. Directions for future research are discussed.

Indexed as

Acceptance and Commitment TherapyAdolescentAnorexia NervosaBody WeightChildFamily RelationsFamily TherapyFemaleHumansMaleParentsAcceptance and commitment therapyAdolescentAnorexia nervosaFamily based treatmentTreatment

Identifiers

PMID25898341
PMCPMC4869854
OpenAlexW2053286678

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.