ArticleEmerging infectious diseases2015
Recent US Case of Variant Creutzfeldt-Jakob Disease-Global Implications.
Article in Emerging infectious diseases, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
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Who cites it
16 citing papers in PubMed.
- Bovine spongiform encephalopathy: A review of current knowledge and challenges.Open veterinary journal · 2025Review
- Variant CJD: Reflections a Quarter of a Century on.Pathogens (Basel, Switzerland) · 2021Review
- Generation of human chronic wasting disease in transgenic mice.Acta neuropathologica communications · 2021Article
- The importance of ongoing international surveillance for Creutzfeldt-Jakob disease.Nature reviews. Neurology · 2021Review
- Prion Diseases.Neurologic clinics · 2018Review
- Recombinant PrPSc shares structural features with brain-derived PrPSc: Insights from limited proteolysis.PLoS pathogens · 2018Article
- Source genotype influence on cross species transmission of transmissible spongiform encephalopathies evaluated by RT-QuIC.PloS one · 2018Article
- Evidence for more cost-effective surveillance options for bovine spongiform encephalopathy (BSE) and scrapie in Great Britain.Euro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin · 2017Article
- Polymorphism at 129 dictates metastable conformations of the human prion protein N-terminal β-sheet.Chemical science · 2017Article
- Detection of prions in blood from patients with variant Creutzfeldt-Jakob disease.Science translational medicine · 2016Article
- A case cluster of variant Creutzfeldt-Jakob disease linked to the Kingdom of Saudi Arabia.Brain : a journal of neurology · 2016Article
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- Prions efficiently cross the intestinal barrier after oral administration: Study of the bioavailability, and cellular and tissue distribution in vivo.Scientific reports · 2016Article
- Article
- Prion Diseases.Continuum (Minneapolis, Minn.) · 2015Review
- Article
Corrections and comments
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Authors and funding
15 authors.
Funding
Abstract
Variant Creutzfeldt-Jakob disease (vCJD) is a rare, fatal prion disease resulting from transmission to humans of the infectious agent of bovine spongiform encephalopathy. We describe the clinical presentation of a recent case of vCJD in the United States and provide an update on diagnostic testing. The location of this patient's exposure is less clear than those in the 3 previously reported US cases, but strong evidence indicates that exposure to contaminated beef occurred outside the United States more than a decade before illness onset. This case exemplifies the persistent risk for vCJD acquired in unsuspected geographic locations and highlights the need for continued global surveillance and awareness to prevent further dissemination of vCJD.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.