Evidence map›Paper›PMID 25897611›Full record

ArticleMonoclonal antibodies in immunodiagnosis and immunotherapy2015

Monoclonal antibody against M protein of spring viremia of carp virus.

Zeming Li, Qi Zhang, Peixiao Luo, Guangxin Liu, Min Wang, Xueqin Liu

Abstract read
In one paragraph

Article in Monoclonal antibodies in immunodiagnosis and immunotherapy, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Cyprinid viral diseases and vaccine development.Fish & shellfish immunology · 2018
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Zeming LiDepartment of Aquatic Animal Medicine, College of Fisheries, Huazhong Agricultural University , Wuhan, Hubei, China .
Qi Zhang
Peixiao Luo
Guangxin Liu
Min Wang
Xueqin Liu

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

M protein of spring viremia of carp virus (SVCV) was expressed in Escherichia coli and then used to immunize BALB/c mice. One monoclonal antibody (5A1) against M protein was generated by fusion of mouse myeloma cell line SP2/0 and spleen lymphocytes from immunized mice. The characterizations of this MAb were confirmed by ELISA (enzyme linked immunosorbent assay), IFA (immunofluorescent assay), and Western blot analysis. All results indicate that MAb 5A1 was specific to SVCV M protein.

Indexed as

AnimalsAntibodies, Monoclonal, Murine-DerivedAntibodies, ViralAntibody SpecificityCarpsEpitope MappingFemaleFluorescent Antibody Technique, IndirectHybridomasMiceMice, Inbred BALB CRhabdoviridaeViral Matrix ProteinsAntibodies, Monoclonal, Murine-DerivedAntibodies, ViralViral Matrix Proteins

Identifiers

PMID25897611
PMCPMC4410279

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.